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SARS-CoV-2 N gene dropout and N gene Ct value shift as indicator for the presence of B.1.1.7 lineage in a commercial multiplex PCR assay

OBJECTIVES: Detection and surveillance of SARS-CoV-2 is of eminent importance, particularly due to the rapid emergence of variants of concern (VOCs). In this study we evaluated if a commercially available quantitative real-time PCR (qRT-PCR) assay can identify SARS-CoV-2 B.1.1.7 lineage samples by a...

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Detalles Bibliográficos
Autores principales: Wollschläger, Paul, Todt, Daniel, Gerlitz, Nadja, Pfaender, Stephanie, Bollinger, Thomas, Sing, Andreas, Dangel, Alexandra, Ackermann, Nickolaus, Korn, Klaus, Ensser, Armin, Steinmann, Eike, Buhl, Michael, Steinmann, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142743/
https://www.ncbi.nlm.nih.gov/pubmed/34044153
http://dx.doi.org/10.1016/j.cmi.2021.05.025

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