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An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate

We report an unusual and rare case of infection from methicillin resistant Staphylococcus aureus (MRSA) producing Panton-Valentine leukocidin in a preterm neonate in NICU. On day of life 8, a preterm baby boy suddenly developed arthritis, giant cutaneous abscesses and an osteomyelitic focus with pou...

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Autores principales: Capasso, Letizia, Cerullo, Julia, Lo Vecchio, Andrea, Coppola, Clara, Lepore, Lorenza, Marra, Valentina, Antonaki, Eleni, Raimondi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142768/
https://www.ncbi.nlm.nih.gov/pubmed/33944831
http://dx.doi.org/10.23750/abm.v92iS1.9885
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author Capasso, Letizia
Cerullo, Julia
Lo Vecchio, Andrea
Coppola, Clara
Lepore, Lorenza
Marra, Valentina
Antonaki, Eleni
Raimondi, Francesco
author_facet Capasso, Letizia
Cerullo, Julia
Lo Vecchio, Andrea
Coppola, Clara
Lepore, Lorenza
Marra, Valentina
Antonaki, Eleni
Raimondi, Francesco
author_sort Capasso, Letizia
collection PubMed
description We report an unusual and rare case of infection from methicillin resistant Staphylococcus aureus (MRSA) producing Panton-Valentine leukocidin in a preterm neonate in NICU. On day of life 8, a preterm baby boy suddenly developed arthritis, giant cutaneous abscesses and an osteomyelitic focus with pour clinical condition. This very aggressive presentation of infection from MRSA push us to test Panton-Valentine leukocidin resulted positive and to test contacts to discover the bearer of the germ. MRSA producing Panton-Valentine leukocidin is an unusual case of infection in preterm neonate that has not been reported elsewhere. A very aggressive sepsis in neonates from Staphilococcus aureus should evoke the need to test Panton-Valentine leukocidin to rapidly establish an appropriate treatment. We underline also the importance to test contacts to establish promptly a decontaminant therapy. (www.actabiomedica.it)
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spelling pubmed-81427682021-05-27 An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate Capasso, Letizia Cerullo, Julia Lo Vecchio, Andrea Coppola, Clara Lepore, Lorenza Marra, Valentina Antonaki, Eleni Raimondi, Francesco Acta Biomed Case Report We report an unusual and rare case of infection from methicillin resistant Staphylococcus aureus (MRSA) producing Panton-Valentine leukocidin in a preterm neonate in NICU. On day of life 8, a preterm baby boy suddenly developed arthritis, giant cutaneous abscesses and an osteomyelitic focus with pour clinical condition. This very aggressive presentation of infection from MRSA push us to test Panton-Valentine leukocidin resulted positive and to test contacts to discover the bearer of the germ. MRSA producing Panton-Valentine leukocidin is an unusual case of infection in preterm neonate that has not been reported elsewhere. A very aggressive sepsis in neonates from Staphilococcus aureus should evoke the need to test Panton-Valentine leukocidin to rapidly establish an appropriate treatment. We underline also the importance to test contacts to establish promptly a decontaminant therapy. (www.actabiomedica.it) Mattioli 1885 2021 2021-04-30 /pmc/articles/PMC8142768/ /pubmed/33944831 http://dx.doi.org/10.23750/abm.v92iS1.9885 Text en Copyright: © 2020 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Case Report
Capasso, Letizia
Cerullo, Julia
Lo Vecchio, Andrea
Coppola, Clara
Lepore, Lorenza
Marra, Valentina
Antonaki, Eleni
Raimondi, Francesco
An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate
title An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate
title_full An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate
title_fullStr An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate
title_full_unstemmed An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate
title_short An unusual aggressive presentation of late onset sepsis due to Staphylococcus Aureus MRSA producing panton-valentine leucocidin in preterm neonate
title_sort unusual aggressive presentation of late onset sepsis due to staphylococcus aureus mrsa producing panton-valentine leucocidin in preterm neonate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142768/
https://www.ncbi.nlm.nih.gov/pubmed/33944831
http://dx.doi.org/10.23750/abm.v92iS1.9885
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