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Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho
Reversible differentiation of vascular smooth muscle cells (VSMCs) plays a critical role in vascular biology and disease. Changes in VSMC differentiation correlate with stiffness of the arterial extracellular matrix (ECM), but causal relationships remain unclear. We show that VSMC plasticity is mech...
Autores principales: | Talwar, Shefali, Kant, Aayush, Xu, Tina, Shenoy, Vivek B., Assoian, Richard K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142933/ https://www.ncbi.nlm.nih.gov/pubmed/33882318 http://dx.doi.org/10.1016/j.celrep.2021.109019 |
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