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Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho

Reversible differentiation of vascular smooth muscle cells (VSMCs) plays a critical role in vascular biology and disease. Changes in VSMC differentiation correlate with stiffness of the arterial extracellular matrix (ECM), but causal relationships remain unclear. We show that VSMC plasticity is mech...

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Detalles Bibliográficos
Autores principales: Talwar, Shefali, Kant, Aayush, Xu, Tina, Shenoy, Vivek B., Assoian, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142933/
https://www.ncbi.nlm.nih.gov/pubmed/33882318
http://dx.doi.org/10.1016/j.celrep.2021.109019

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