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Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds
Atypical porcine pestivirus (APPV) was first discovered in North America in 2015 and was later shown to be associated with congenital tremor (CT) in piglets. CT is an occasional challenge in some Danish sow herds. Therefore, we initiated an observational case control study to clarify a possible rela...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142981/ https://www.ncbi.nlm.nih.gov/pubmed/33919031 http://dx.doi.org/10.3390/v13050717 |
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author | Pedersen, Kasper Kristensen, Charlotte Sonne Strandbygaard, Bertel Bøtner, Anette Rasmussen, Thomas Bruun |
author_facet | Pedersen, Kasper Kristensen, Charlotte Sonne Strandbygaard, Bertel Bøtner, Anette Rasmussen, Thomas Bruun |
author_sort | Pedersen, Kasper |
collection | PubMed |
description | Atypical porcine pestivirus (APPV) was first discovered in North America in 2015 and was later shown to be associated with congenital tremor (CT) in piglets. CT is an occasional challenge in some Danish sow herds. Therefore, we initiated an observational case control study to clarify a possible relationship between CT and APPV in Danish pig production. Blood samples were collected from piglets affected by CT (n = 55) in ten different sow herds and from healthy piglets in five sow herds without a history of CT piglets (n = 25), as well as one sow herd with a sporadic occurrence of CT (n = 5). APPV was detected by RT-qPCR in all samples from piglets affected by CT and in three out of five samples from piglets in the herd with a sporadic occurrence of CT. In the herds without a history of CT, only one out of 25 piglets were positive for APPV. In addition, farmers or veterinarians in CT-affected herds were asked about their experience of the issue. CT is most often seen in gilt litters, and a substantial increase in pre-weaning mortality is only observed in severe cases. According to our investigations, APPV is a common finding in piglets suffering from CT in Denmark. |
format | Online Article Text |
id | pubmed-8142981 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81429812021-05-25 Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds Pedersen, Kasper Kristensen, Charlotte Sonne Strandbygaard, Bertel Bøtner, Anette Rasmussen, Thomas Bruun Viruses Article Atypical porcine pestivirus (APPV) was first discovered in North America in 2015 and was later shown to be associated with congenital tremor (CT) in piglets. CT is an occasional challenge in some Danish sow herds. Therefore, we initiated an observational case control study to clarify a possible relationship between CT and APPV in Danish pig production. Blood samples were collected from piglets affected by CT (n = 55) in ten different sow herds and from healthy piglets in five sow herds without a history of CT piglets (n = 25), as well as one sow herd with a sporadic occurrence of CT (n = 5). APPV was detected by RT-qPCR in all samples from piglets affected by CT and in three out of five samples from piglets in the herd with a sporadic occurrence of CT. In the herds without a history of CT, only one out of 25 piglets were positive for APPV. In addition, farmers or veterinarians in CT-affected herds were asked about their experience of the issue. CT is most often seen in gilt litters, and a substantial increase in pre-weaning mortality is only observed in severe cases. According to our investigations, APPV is a common finding in piglets suffering from CT in Denmark. MDPI 2021-04-21 /pmc/articles/PMC8142981/ /pubmed/33919031 http://dx.doi.org/10.3390/v13050717 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pedersen, Kasper Kristensen, Charlotte Sonne Strandbygaard, Bertel Bøtner, Anette Rasmussen, Thomas Bruun Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds |
title | Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds |
title_full | Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds |
title_fullStr | Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds |
title_full_unstemmed | Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds |
title_short | Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds |
title_sort | detection of atypical porcine pestivirus in piglets from danish sow herds |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142981/ https://www.ncbi.nlm.nih.gov/pubmed/33919031 http://dx.doi.org/10.3390/v13050717 |
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