High Throughput Virtual Screening and Molecular Dynamics Simulation for Identifying a Putative Inhibitor of Bacterial CTX-M-15

Background: Multidrug resistant bacteria are a major therapeutic challenge. CTX-M-type enzymes are an important group of class A extended-spectrum β-lactamases (ESBLs). ESBLs are the enzymes that arm bacterial pathogens with drug resistance to an array of antibiotics, notably the advanced-generation...

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Detalles Bibliográficos
Autores principales: Shakil, Shazi, Rizvi, Syed M. Danish, Greig, Nigel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143117/
https://www.ncbi.nlm.nih.gov/pubmed/33919115
http://dx.doi.org/10.3390/antibiotics10050474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143117/
https://www.ncbi.nlm.nih.gov/pubmed/33919115
http://dx.doi.org/10.3390/antibiotics10050474

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