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Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes

Neoadjuvant chemotherapy is increasingly being employed in the management of breast cancer patients. Efforts and resources have been devoted over the years to the search for an optimal strategy that can improve outcomes in the neoadjuvant setting. Today, a multidisciplinary approach with the applica...

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Autores principales: Di Leone, Alba, Terribile, Daniela, Magno, Stefano, Sanchez, Alejandro Martin, Scardina, Lorenzo, Mason, Elena Jane, D’Archi, Sabatino, Maggiore, Claudia, Rossi, Cristina, Di Micco, Annalisa, Carnevale, Stefania, Paris, Ida, Marazzi, Fabio, Masiello, Valeria, Orlandi, Armando, Palazzo, Antonella, Fabi, Alessandra, Masetti, Riccardo, Franceschini, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143137/
https://www.ncbi.nlm.nih.gov/pubmed/33919061
http://dx.doi.org/10.3390/jpm11050324
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author Di Leone, Alba
Terribile, Daniela
Magno, Stefano
Sanchez, Alejandro Martin
Scardina, Lorenzo
Mason, Elena Jane
D’Archi, Sabatino
Maggiore, Claudia
Rossi, Cristina
Di Micco, Annalisa
Carnevale, Stefania
Paris, Ida
Marazzi, Fabio
Masiello, Valeria
Orlandi, Armando
Palazzo, Antonella
Fabi, Alessandra
Masetti, Riccardo
Franceschini, Gianluca
author_facet Di Leone, Alba
Terribile, Daniela
Magno, Stefano
Sanchez, Alejandro Martin
Scardina, Lorenzo
Mason, Elena Jane
D’Archi, Sabatino
Maggiore, Claudia
Rossi, Cristina
Di Micco, Annalisa
Carnevale, Stefania
Paris, Ida
Marazzi, Fabio
Masiello, Valeria
Orlandi, Armando
Palazzo, Antonella
Fabi, Alessandra
Masetti, Riccardo
Franceschini, Gianluca
author_sort Di Leone, Alba
collection PubMed
description Neoadjuvant chemotherapy is increasingly being employed in the management of breast cancer patients. Efforts and resources have been devoted over the years to the search for an optimal strategy that can improve outcomes in the neoadjuvant setting. Today, a multidisciplinary approach with the application of evidence-based medicine is considered the gold standard for the improvement of oncological results and patient satisfaction. However, several clinical complications and psychological issues due to various factors can arise during neoadjuvant therapy and undermine outcomes. To ensure that health care needs are adequately addressed, clinicians must consider that women with breast cancer have a high risk of developing “unmet needs” during treatment, and often require a clinical intervention or additional care resources to limit possible complications and psychological issues that can occur during neoadjuvant treatment. This work describes a multidisciplinary model developed at “Fondazione Policlinico Universitario Agostino Gemelli” (FPG) in Rome in an effort to optimize treatment, ease the application of evidence-based medicine, and improve patient quality of life in the neoadjuvant setting. In developing our model, our main goal was to adequately meet patient needs while preventing high levels of distress.
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spelling pubmed-81431372021-05-25 Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes Di Leone, Alba Terribile, Daniela Magno, Stefano Sanchez, Alejandro Martin Scardina, Lorenzo Mason, Elena Jane D’Archi, Sabatino Maggiore, Claudia Rossi, Cristina Di Micco, Annalisa Carnevale, Stefania Paris, Ida Marazzi, Fabio Masiello, Valeria Orlandi, Armando Palazzo, Antonella Fabi, Alessandra Masetti, Riccardo Franceschini, Gianluca J Pers Med Review Neoadjuvant chemotherapy is increasingly being employed in the management of breast cancer patients. Efforts and resources have been devoted over the years to the search for an optimal strategy that can improve outcomes in the neoadjuvant setting. Today, a multidisciplinary approach with the application of evidence-based medicine is considered the gold standard for the improvement of oncological results and patient satisfaction. However, several clinical complications and psychological issues due to various factors can arise during neoadjuvant therapy and undermine outcomes. To ensure that health care needs are adequately addressed, clinicians must consider that women with breast cancer have a high risk of developing “unmet needs” during treatment, and often require a clinical intervention or additional care resources to limit possible complications and psychological issues that can occur during neoadjuvant treatment. This work describes a multidisciplinary model developed at “Fondazione Policlinico Universitario Agostino Gemelli” (FPG) in Rome in an effort to optimize treatment, ease the application of evidence-based medicine, and improve patient quality of life in the neoadjuvant setting. In developing our model, our main goal was to adequately meet patient needs while preventing high levels of distress. MDPI 2021-04-21 /pmc/articles/PMC8143137/ /pubmed/33919061 http://dx.doi.org/10.3390/jpm11050324 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Di Leone, Alba
Terribile, Daniela
Magno, Stefano
Sanchez, Alejandro Martin
Scardina, Lorenzo
Mason, Elena Jane
D’Archi, Sabatino
Maggiore, Claudia
Rossi, Cristina
Di Micco, Annalisa
Carnevale, Stefania
Paris, Ida
Marazzi, Fabio
Masiello, Valeria
Orlandi, Armando
Palazzo, Antonella
Fabi, Alessandra
Masetti, Riccardo
Franceschini, Gianluca
Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes
title Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes
title_full Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes
title_fullStr Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes
title_full_unstemmed Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes
title_short Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes
title_sort neoadjuvant chemotherapy in breast cancer: an advanced personalized multidisciplinary prehabilitation model (apmp-m) to optimize outcomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143137/
https://www.ncbi.nlm.nih.gov/pubmed/33919061
http://dx.doi.org/10.3390/jpm11050324
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