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Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages

Background: Alveolar macrophages (AMs) are resident inflammatory cells in the lung that serve as early sentinels of infection or injury. We have identified thioredoxin reductase 1 inhibition by gold compounds increases activation of nuclear factor erythroid 2-related factor 2 (NRF2)-dependent pathwa...

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Detalles Bibliográficos
Autores principales:	Wall, Stephanie B., Li, Rui, Butler, Brittany, Burg, Ashley R., Tse, Hubert M., Larson-Casey, Jennifer L., Carter, A. Brent, Wright, Clyde J., Rogers, Lynette K., Tipple, Trent E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143169/ https://www.ncbi.nlm.nih.gov/pubmed/33919055 http://dx.doi.org/10.3390/antiox10050632

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