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Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target
SIMPLE SUMMARY: A compact neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. The source comprises an original design tandem accelerator, solid lithium target, and a neutron beam shaping assembly. The neutron source is capable of producing...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143170/ https://www.ncbi.nlm.nih.gov/pubmed/33919153 http://dx.doi.org/10.3390/biology10050350 |
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author | Taskaev, Sergey Berendeev, Evgenii Bikchurina, Marina Bykov, Timofey Kasatov, Dmitrii Kolesnikov, Iaroslav Koshkarev, Alexey Makarov, Aleksandr Ostreinov, Georgii Porosev, Vyacheslav Savinov, Sergey Shchudlo, Ivan Sokolova, Evgeniia Sorokin, Igor Sycheva, Tatiana Verkhovod, Gleb |
author_facet | Taskaev, Sergey Berendeev, Evgenii Bikchurina, Marina Bykov, Timofey Kasatov, Dmitrii Kolesnikov, Iaroslav Koshkarev, Alexey Makarov, Aleksandr Ostreinov, Georgii Porosev, Vyacheslav Savinov, Sergey Shchudlo, Ivan Sokolova, Evgeniia Sorokin, Igor Sycheva, Tatiana Verkhovod, Gleb |
author_sort | Taskaev, Sergey |
collection | PubMed |
description | SIMPLE SUMMARY: A compact neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. The source comprises an original design tandem accelerator, solid lithium target, and a neutron beam shaping assembly. The neutron source is capable of producing the high neutron flux in various energy ranges, from thermal to fast, for boron neutron capture therapy, as well as for other applications. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The Boron Neutron Capture Therapy (BNCT) technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China). ABSTRACT: A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The proton beam energy can be varied within a range of 0.6–2.3 MeV, keeping a high-energy stability of 0.1%. The beam current can also be varied in a wide range (from 0.3 mA to 10 mA) with high current stability (0.4%). In the device, neutron flux is generated as a result of the (7)Li(p,n)(7)Be threshold reaction. A beam-shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The BNCT technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China). |
format | Online Article Text |
id | pubmed-8143170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81431702021-05-25 Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target Taskaev, Sergey Berendeev, Evgenii Bikchurina, Marina Bykov, Timofey Kasatov, Dmitrii Kolesnikov, Iaroslav Koshkarev, Alexey Makarov, Aleksandr Ostreinov, Georgii Porosev, Vyacheslav Savinov, Sergey Shchudlo, Ivan Sokolova, Evgeniia Sorokin, Igor Sycheva, Tatiana Verkhovod, Gleb Biology (Basel) Article SIMPLE SUMMARY: A compact neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. The source comprises an original design tandem accelerator, solid lithium target, and a neutron beam shaping assembly. The neutron source is capable of producing the high neutron flux in various energy ranges, from thermal to fast, for boron neutron capture therapy, as well as for other applications. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The Boron Neutron Capture Therapy (BNCT) technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China). ABSTRACT: A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The proton beam energy can be varied within a range of 0.6–2.3 MeV, keeping a high-energy stability of 0.1%. The beam current can also be varied in a wide range (from 0.3 mA to 10 mA) with high current stability (0.4%). In the device, neutron flux is generated as a result of the (7)Li(p,n)(7)Be threshold reaction. A beam-shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The BNCT technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China). MDPI 2021-04-21 /pmc/articles/PMC8143170/ /pubmed/33919153 http://dx.doi.org/10.3390/biology10050350 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Taskaev, Sergey Berendeev, Evgenii Bikchurina, Marina Bykov, Timofey Kasatov, Dmitrii Kolesnikov, Iaroslav Koshkarev, Alexey Makarov, Aleksandr Ostreinov, Georgii Porosev, Vyacheslav Savinov, Sergey Shchudlo, Ivan Sokolova, Evgeniia Sorokin, Igor Sycheva, Tatiana Verkhovod, Gleb Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target |
title | Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target |
title_full | Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target |
title_fullStr | Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target |
title_full_unstemmed | Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target |
title_short | Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target |
title_sort | neutron source based on vacuum insulated tandem accelerator and lithium target |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143170/ https://www.ncbi.nlm.nih.gov/pubmed/33919153 http://dx.doi.org/10.3390/biology10050350 |
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