Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice

Although macroautophagy/autophagy deficiency causes degenerative diseases, the deletion of essential autophagy genes in adipocytes paradoxically reduces body weight. Brown adipose tissue (BAT) plays an important role in body weight regulation and metabolic control. However, the key cellular mechanis...

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Detalles Bibliográficos
Autores principales: Ko, Myoung Seok, Yun, Ji Young, Baek, In-Jeoung, Jang, Jung Eun, Hwang, Jung Jin, Lee, Seung Eun, Heo, Seung-Ho, Bader, David A., Lee, Chul-Ho, Han, Jaeseok, Moon, Jong-Seok, Lee, Jae Man, Hong, Eun-Gyoung, Lee, In-Kyu, Kim, Seong Who, Park, Joong Yeol, Hartig, Sean M., Kang, Un Jung, Moore, David D., Koh, Eun Hee, Lee, Ki-up
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143238/
https://www.ncbi.nlm.nih.gov/pubmed/32400277
http://dx.doi.org/10.1080/15548627.2020.1753002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143238/
https://www.ncbi.nlm.nih.gov/pubmed/32400277
http://dx.doi.org/10.1080/15548627.2020.1753002

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