Cargando…

Somatic Copy-Number Alterations in Plasma Circulating Tumor DNA from Advanced EGFR-Mutated Lung Adenocarcinoma Patients

Background: To assess the clinical relevance of genome-wide somatic copy-number alterations (SCNAs) in plasma circulating tumor DNA (ctDNA) from advanced epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma patients. Methods: We included 43 patients with advanced EGFR T790M-positive l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buder, Anna, Heitzer, Ellen, Waldispühl-Geigl, Julie, Weber, Sabrina, Moser, Tina, Hochmair, Maximilian J., Hackner, Klaus, Errhalt, Peter, Setinek, Ulrike, Filipits, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143372/ https://www.ncbi.nlm.nih.gov/pubmed/33919291 http://dx.doi.org/10.3390/biom11050618

Ejemplares similares

EGFR mutation tracking predicts survival in advanced EGFR-mutated non-small cell lung cancer patients treated with osimertinib
por: Buder, Anna, et al.
Publicado: (2020)

Detection of EGFR Activating and Resistance Mutations by Droplet Digital PCR in Sputum of EGFR-Mutated NSCLC Patients
por: Hackner, Klaus, et al.
Publicado: (2021)

EGFR Mutations in Cell-free Plasma DNA from Patients with Advanced Lung Adenocarcinoma: Improved Detection by Droplet Digital PCR
por: Buder, Anna, et al.
Publicado: (2019)

The Allele Frequency of EGFR Mutations Predicts Survival in Advanced EGFR T790M-Positive Non-small Cell Lung Cancer Patients Treated with Osimertinib
por: Buder, Anna, et al.
Publicado: (2020)

Liquid-Biopsy-Based Identification of EGFR T790M Mutation-Mediated Resistance to Afatinib Treatment in Patients with Advanced EGFR Mutation-Positive NSCLC, and Subsequent Response to Osimertinib
por: Hochmair, Maximilian J., et al.
Publicado: (2018)

Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patients
por: Hallermayr, Ariane, et al.
Publicado: (2022)

Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer
por: Heitzer, Ellen, et al.
Publicado: (2013)

Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma
por: Muñoz-Hidalgo, Lisandra, et al.
Publicado: (2019)

Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing
por: Heitzer, Ellen, et al.
Publicado: (2013)

CNValidator: validating somatic copy-number inference
por: Smith, Lucian P, et al.
Publicado: (2019)

On-treatment measurements of circulating tumor DNA during FOLFOX therapy in patients with colorectal cancer
por: Moser, Tina, et al.
Publicado: (2020)

Ratio of carcinoembryonic antigen in pleural fluid and serum for the diagnosis of malignant pleural effusion
por: Hackner, Klaus, et al.
Publicado: (2019)

Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells
por: Court, Colin M., et al.
Publicado: (2020)

Reliability of algorithmic somatic copy number alteration detection from targeted capture data
por: Rieber, Nora, et al.
Publicado: (2017)

Circulating tumor cells and DNA as liquid biopsies
por: Heitzer, Ellen, et al.
Publicado: (2013)

Single circulating tumor cell sequencing for monitoring
por: Auer, Martina, et al.
Publicado: (2013)

Pan-cancer patterns of somatic copy-number alteration
por: Zack, Travis I., et al.
Publicado: (2013)

Robustness of the Autophagy Pathway to Somatic Copy Number Losses
por: Polo, Pierfrancesco, et al.
Publicado: (2022)

Somatic Copy Number Alteration in Circulating Tumor DNA for Monitoring of Pediatric Patients with Cancer
por: Ruas, Juliana Silveira, et al.
Publicado: (2023)

Later-Line Treatment with Lorlatinib in ALK- and ROS1-Rearrangement-Positive NSCLC: A Retrospective, Multicenter Analysis
por: Hochmair, Maximilian J., et al.
Publicado: (2020)

The landscape of somatic copy-number alteration across human cancers
por: Beroukhim, Rameen, et al.
Publicado: (2010)

Controlled Somatic and Germline Copy Number Variation in the Mouse Model
por: Hérault, Yann, et al.
Publicado: (2010)

SCNVSim: somatic copy number variation and structure variation simulator
por: Qin, Maochun, et al.
Publicado: (2015)

Somatic mosaicism for copy-neutral loss of heterozygosity and DNA copy number variations in the human genome
por: Žilina, Olga, et al.
Publicado: (2015)

Somatic copy number variant load in neurons of healthy controls and Alzheimer’s disease patients
por: Turan, Zeliha Gözde, et al.
Publicado: (2022)

The Human Genome Puzzle – the Role of Copy Number Variation in Somatic Mosaicism
por: Mkrtchyan, Hasmik, et al.
Publicado: (2010)

Short somatic alterations at the site of copy number variation in breast cancer
por: Murakami, Fumi, et al.
Publicado: (2020)

Subclonal somatic copy number alterations emerge and dominate in recurrent osteosarcoma
por: Kinnaman, Michael D., et al.
Publicado: (2023)

Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma
por: Kinnaman, Michael D., et al.
Publicado: (2023)

The potential of liquid biopsies for the early detection of cancer
por: Heitzer, Ellen, et al.
Publicado: (2017)

Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas
por: Liang, Zhiyong, et al.
Publicado: (2010)

Correlation of EGFR expression, gene copy number and clinicopathological status in NSCLC
por: Gaber, Rania, et al.
Publicado: (2014)

LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations
por: Lakatos, Eszter, et al.
Publicado: (2021)

cnvCurator: an interactive visualization and editing tool for somatic copy number variations
por: Ma, Lingnan, et al.
Publicado: (2015)

Validation of Customized Cancer Panel for Detecting Somatic Mutations and Copy Number Alterations
por: Choi, Su-Hye, et al.
Publicado: (2017)

Association Analysis of Somatic Copy Number Alteration Burden With Breast Cancer Survival
por: Zhang, Linfan, et al.
Publicado: (2018)

Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients
por: Schumacher, Steven E., et al.
Publicado: (2017)

Identification and Characterization of MicroRNAs Associated with Somatic Copy Number Alterations in Cancer
por: Soh, Jihee, et al.
Publicado: (2018)

The Landscape of Somatic Copy Number Alterations in Head and Neck Squamous Cell Carcinoma
por: Yang, Jian, et al.
Publicado: (2020)

CNV Radar: an improved method for somatic copy number alteration characterization in oncology
por: Soong, David, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_010acjuhrjr901ovf2584q1n3a