Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images

Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is used to diagnose and manage ophthalmic diseases including glaucoma. We present the first large-scale genome-wide association study of inner retinal morphology using phenotypes derived from OCT images of 31,434 UK Bi...

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Detalles Bibliográficos
Autores principales: Currant, Hannah, Hysi, Pirro, Fitzgerald, Tomas W., Gharahkhani, Puya, Bonnemaijer, Pieter W. M., Senabouth, Anne, Hewitt, Alex W., Atan, Denize, Aung, Tin, Charng, Jason, Choquet, Hélène, Craig, Jamie, Khaw, Peng T., Klaver, Caroline C. W., Kubo, Michiaki, Ong, Jue-Sheng, Pasquale, Louis R., Reisman, Charles A., Daniszewski, Maciej, Powell, Joseph E., Pébay, Alice, Simcoe, Mark J., Thiadens, Alberta A. H. J., van Duijn, Cornelia M., Yazar, Seyhan, Jorgenson, Eric, MacGregor, Stuart, Hammond, Chris J., Mackey, David A., Wiggs, Janey L., Foster, Paul J., Patel, Praveen J., Birney, Ewan, Khawaja, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143408/
https://www.ncbi.nlm.nih.gov/pubmed/33979322
http://dx.doi.org/10.1371/journal.pgen.1009497

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