Cargando…

Patterns of selection against centrosome amplification in human cell lines

The presence of extra centrioles, termed centrosome amplification, is a hallmark of cancer. The distribution of centriole numbers within a cancer cell population appears to be at an equilibrium maintained by centriole overproduction and selection, reminiscent of mutation-selection balance. It is unk...

Descripción completa

Detalles Bibliográficos
Autores principales: Dias Louro, Marco António, Bettencourt-Dias, Mónica, Bank, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143425/
https://www.ncbi.nlm.nih.gov/pubmed/33979341
http://dx.doi.org/10.1371/journal.pcbi.1008765

Ejemplares similares