Cargando…

Overcoming the Challenges of High Quality RNA Extraction from Core Needle Biopsy

The use of gene expression profiling (GEP) in cancer management is rising, as GEP can be used for disease classification and diagnosis, tailoring treatment to underlying genetic determinants of pharmacological response, monitoring of therapy response, and prognosis. However, the reliability of GEP h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Locy, Hanne, Correa, Rohann J.M., Autaers, Dorien, Schiettecatte, Ann, Jonckheere, Jan, Waelput, Wim, Cras, Louise, Brock, Stefanie, Verhulst, Stefaan, Kwan, Keith, Vanhoeij, Marian, Thielemans, Kris, Breckpot, Karine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143498/ https://www.ncbi.nlm.nih.gov/pubmed/33922016 http://dx.doi.org/10.3390/biom11050621

Ejemplares similares

Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer: A Proposal for Combining Immunohistochemistry and Gene Expression Analysis to Refine Scoring
por: Locy, Hanne, et al.
Publicado: (2022)

An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8(+) T cells
por: de Mey, Wout, et al.
Publicado: (2023)

A synthetic DNA template for fast manufacturing of versatile single epitope mRNA
por: de Mey, Wout, et al.
Publicado: (2022)

A rare cause of unilateral breast swelling in a male infant caused by fibrous hamartoma of infancy combined with pseudoangiomatous stromal hyperplasia
por: Jonckheere, Jan, et al.
Publicado: (2019)

The role of SMAC mimetics in regulation of tumor cell death and immunity
por: Emeagi, Perpetua U., et al.
Publicado: (2012)

mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic
por: Van Lint, Sandra, et al.
Publicado: (2013)

Design of an Optimized Wilms' Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo
por: Benteyn, Daphné, et al.
Publicado: (2013)

RNA in Cancer Immunotherapy: Unlocking the Potential of the Immune System
por: De Mey, Wout, et al.
Publicado: (2022)

Immunomodulation of the Tumor Microenvironment: Turn Foe Into Friend
por: Locy, Hanne, et al.
Publicado: (2018)

Neo-Antigen mRNA Vaccines
por: Esprit, Arthur, et al.
Publicado: (2020)

Overcoming HLA restriction in clinical trials: Immune monitoring of mRNA-loaded DC therapy
por: Van Nuffel, An M.T., et al.
Publicado: (2012)

TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy
por: De Ridder, Kirsten, et al.
Publicado: (2022)

Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity
por: Van der Jeught, Kevin, et al.
Publicado: (2014)

Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production
por: Broos, Katrijn, et al.
Publicado: (2019)

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon
por: Broos, Katrijn, et al.
Publicado: (2016)

Immunogenicity of targeted lentivectors
por: Goyvaerts, Cleo, et al.
Publicado: (2014)

Targeting the tumor microenvironment to enhance antitumor immune responses
por: Van der Jeught, Kevin, et al.
Publicado: (2014)

Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours
por: Bialkowski, Lukasz, et al.
Publicado: (2016)

Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade
por: Lecocq, Quentin, et al.
Publicado: (2021)

Stereotactic Body Radiotherapy: Hitting Harder, Faster, and Smarter in High-Risk Prostate Cancer
por: Correa, Rohann J. M., et al.
Publicado: (2022)

Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177–Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model
por: Ertveldt, Thomas, et al.
Publicado: (2022)

Leptin Is an Endogenous Protective Protein against the Toxicity Exerted by Tumor Necrosis Factor
por: Takahashi, Nozomi, et al.
Publicado: (1999)

Overcoming pubic arch interference in prostate brachytherapy using steerable needles
por: de Vries, Martijn, et al.
Publicado: (2022)

Digital Pathology Data Brokerage: A Standard Recommendation for Complex Digital Pathology Information Web-Services
por: Anagnostakis, Aristidis, et al.
Publicado: (2014)

Pros and Cons of Antigen-Presenting Cell Targeted Tumor Vaccines
por: Goyvaerts, Cleo, et al.
Publicado: (2015)

The Journey of in vivo Virus Engineered Dendritic Cells From Bench to Bedside: A Bumpy Road
por: Goyvaerts, Cleo, et al.
Publicado: (2018)

Commentary: Immunogenic Cell Death and Immunotherapy of Multiple Myeloma
por: Maes, Ken, et al.
Publicado: (2019)

A Framework for Assuring the Safety, Training, Evaluation, and Wellness of Radiation Oncology Residents During the COVID-19 Pandemic (ASTEROiD-COVID19)
por: Goodman, Christopher D., et al.
Publicado: (2021)

Using a Novel Whole Slide Imaging Software Platform for an International Multicenter Validation Study to Assess the Histological Growth Pattern of Liver Metastases
por: Sucaet, Yves, et al.
Publicado: (2014)

Remote Contouring and Virtual Review During the COVID-19 Pandemic (RECOVR-COVID19): Results of a Quality Improvement Initiative for Virtual Resident Training in Radiation Oncology
por: Arifin, Andrew J., et al.
Publicado: (2021)

Overcoming MCL-1-driven adaptive resistance to targeted therapies
por: Wood, Kris C.
Publicado: (2020)

The global impact of open data: key findings from detailed case studies around the world
por: Young, Andrew, et al.
Publicado: (2016)

Identifying and addressing data asymmetries so as to enable (better) science
por: Verhulst, Stefaan, et al.
Publicado: (2022)

Beclin-1 expression is retained in high-grade serous ovarian cancer yet is not essential for autophagy induction in vitro
por: Correa, Rohann J. M., et al.
Publicado: (2015)

122: Remote Contouring and Virtual Review During the COVID-19 Pandemic (RECOVR-COVID19): Results of a Quality Improvement Initiative for Virtual Resident Training in Radiation Oncology
por: Arifin, Andrew, et al.
Publicado: (2021)

Belgian twins born with the Gamma variant of SARS-CoV-2: Transplacental versus intrapartum transmission?
por: Massa, Hanne, et al.
Publicado: (2021)

A Mediator Role For Metallothionein in Tumor Necrosis Factor–induced Lethal Shock
por: Waelput, Wim, et al.
Publicado: (2001)

Utility of Islet Cell Preparations From Donor Pancreases After Euthanasia
por: De Paep, Diedert L., et al.
Publicado: (2022)

Chitin Nanowhisker Aerogels
por: Heath, Lindy, et al.
Publicado: (2013)

Efficient Depolymerization of Glass Fiber Reinforced PET Composites
por: Rubio Arias, Jose Jonathan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kli8bsfcmlotvpcvtu60dhq9j2