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Thymoquinone Is a Multitarget Single Epidrug That Inhibits the UHRF1 Protein Complex
Silencing of tumor suppressor genes (TSGs) through epigenetic mechanisms, mainly via abnormal promoter DNA methylation, is considered a main mechanism of tumorigenesis. The abnormal DNA methylation profiles are transmitted from the cancer mother cell to the daughter cells through the involvement of...
Autores principales: | Abdullah, Omeima, Omran, Ziad, Hosawi, Salman, Hamiche, Ali, Bronner, Christian, Alhosin, Mahmoud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143546/ https://www.ncbi.nlm.nih.gov/pubmed/33922029 http://dx.doi.org/10.3390/genes12050622 |
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