Cargando…

Identification of 15 lncRNAs Signature for Predicting Survival Benefit of Advanced Melanoma Patients Treated with Anti-PD-1 Monotherapy

The blockade of programmed cell death protein 1 (PD-1) as monotherapy has been widely used in melanoma, but to identify melanoma patients with survival benefit from anti-PD-1 monotherapy is still a big challenge. There is an urgent need for prognostic signatures improving the prediction of immunothe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Jian-Guo, Liang, Bo, Liu, Jian-Guo, Jin, Su-Han, He, Si-Si, Frey, Benjamin, Gu, Ning, Fietkau, Rainer, Hecht, Markus, Ma, Hu, Gaipl, Udo S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143567/ https://www.ncbi.nlm.nih.gov/pubmed/33922038 http://dx.doi.org/10.3390/cells10050977

Ejemplares similares

Identification and characterization of circular RNAs as novel putative biomarkers to predict anti-PD-1 monotherapy response in metastatic melanoma patients – Knowledge from two independent international studies
por: Zhou, Jian-Guo, et al.
Publicado: (2023)

Chemoradiation Increases PD-L1 Expression in Certain Melanoma and Glioblastoma Cells
por: Derer, Anja, et al.
Publicado: (2016)

Identification of an endogenous retroviral signature to predict anti-PD1 response in advanced clear cell renal cell carcinoma: an integrated analysis of three clinical trials
por: Zhou, Jian-Guo, et al.
Publicado: (2022)

Immune biological rationales for the design of combined radio- and immunotherapies
por: Hader, Michael, et al.
Publicado: (2020)

Prospective Evaluation of All-lesion Versus Single-lesion Radiotherapy in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors
por: Schubert, Philipp, et al.
Publicado: (2020)

Definitive Radiochemotherapie von lokal fortgeschrittenen Kopf-Hals-Tumoren in Kombination mit Immuncheckpointinhibition – neue Konzepte gefragt
por: Hecht, Markus, et al.
Publicado: (2021)

Prospective development and validation of a liquid immune profile-based signature (LIPS) to predict response of patients with recurrent/metastatic cancer to immune checkpoint inhibitors
por: Zhou, Jian-Guo, et al.
Publicado: (2021)

Questionnaire-based detection of immune-related adverse events in cancer patients treated with PD-1/PD-L1 immune checkpoint inhibitors
por: Griewing, Luisa Maria, et al.
Publicado: (2021)

Development of a Modular Assay for Detailed Immunophenotyping of Peripheral Human Whole Blood Samples by Multicolor Flow Cytometry
por: Rühle, Paul F., et al.
Publicado: (2016)

Elucidation of the Application of Blood Test Biomarkers to Predict Immune-Related Adverse Events in Atezolizumab-Treated NSCLC Patients Using Machine Learning Methods
por: Zhou, Jian-Guo, et al.
Publicado: (2022)

Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints
por: Deloch, Lisa, et al.
Publicado: (2018)

The Role of LncRNAs in Uveal Melanoma
por: Milán-Rois, Paula, et al.
Publicado: (2021)

lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis
por: Chen, Wen‐Kang, et al.
Publicado: (2016)

Radio-Immunotherapy-Induced Immunogenic Cancer Cells as Basis for Induction of Systemic Anti-Tumor Immune Responses – Pre-Clinical Evidence and Ongoing Clinical Applications
por: Derer, Anja, et al.
Publicado: (2015)

Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose
por: Deloch, Lisa, et al.
Publicado: (2019)

Modern Radiotherapy Concepts and the Impact of Radiation on Immune Activation
por: Deloch, Lisa, et al.
Publicado: (2016)

Combinations of Radiotherapy with Vaccination and Immune Checkpoint Inhibition Differently Affect Primary and Abscopal Tumor Growth and the Tumor Microenvironment
por: Rückert, Michael, et al.
Publicado: (2021)

Tumor-specific radiosensitizing effect of the ATM inhibitor AZD0156 in melanoma cells with low toxicity to healthy fibroblasts
por: Scheper, Julian, et al.
Publicado: (2022)

Low Dose Radiation Therapy, Particularly with 0.5 Gy, Improves Pain in Degenerative Joint Disease of the Fingers: Results of a Retrospective Analysis
por: Donaubauer, Anna-Jasmina, et al.
Publicado: (2020)

The Influence of Radiation on Bone and Bone Cells—Differential Effects on Osteoclasts and Osteoblasts
por: Donaubauer, Anna-Jasmina, et al.
Publicado: (2020)

Definition of a new blood cell count score for early survival prediction for non-small cell lung cancer patients treated with atezolizumab: Integrated analysis of four multicenter clinical trials
por: Zhou, Jian-Guo, et al.
Publicado: (2022)

Development and validation of a ferroptosis-related lncRNAs signature to predict prognosis and microenvironment for melanoma
por: Ping, Shuai, et al.
Publicado: (2022)

Metabolism‐related lncRNAs signature to predict the prognosis of colon adenocarcinoma
por: Sun, Yimin, et al.
Publicado: (2022)

Bioinformatic Analyses of the Ferroptosis-Related lncRNAs Signature for Ovarian Cancer
por: Zheng, Jianfeng, et al.
Publicado: (2022)

Clinically Relevant Radiation Exposure Differentially Impacts Forms of Cell Death in Human Cells of the Innate and Adaptive Immune System
por: Falcke, Sylvia E., et al.
Publicado: (2018)

Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines
por: Schatz, Julia, et al.
Publicado: (2022)

The role of lncRNAs in the tumor microenvironment and immunotherapy of melanoma
por: Zhou, Wencheng, et al.
Publicado: (2022)

Low-Dose Radiotherapy Leads to a Systemic Anti-Inflammatory Shift in the Pre-Clinical K/BxN Serum Transfer Model and Reduces Osteoarthritic Pain in Patients
por: Weissmann, Thomas, et al.
Publicado: (2022)

Epitranscriptomic Signatures in lncRNAs and Their Possible Roles in Cancer
por: Dinescu, Sorina, et al.
Publicado: (2019)

A Ferroptosis-Related lncRNAs Signature Predicts Prognosis of Colon Adenocarcinoma
por: Guo, Ying, et al.
Publicado: (2023)

Modulations in the Peripheral Immune System of Glioblastoma Patient Is Connected to Therapy and Tumor Progression—A Case Report from the IMMO-GLIO-01 Trial
por: Rühle, Paul F., et al.
Publicado: (2017)

Hypofractionated Radiotherapy Upregulates Several Immune Checkpoint Molecules in Head and Neck Squamous Cell Carcinoma Cells Independently of the HPV Status While ICOS-L Is Upregulated Only on HPV-Positive Cells
por: Wimmer, Sebastian, et al.
Publicado: (2021)

Modulation of radiochemoimmunotherapy-induced B16 melanoma cell death by the pan-caspase inhibitor zVAD-fmk induces anti-tumor immunity in a HMGB1-, nucleotide- and T-cell-dependent manner
por: Werthmöller, N, et al.
Publicado: (2015)

The in vitro immunogenic potential of caspase-3 proficient breast cancer cells with basal low immunogenicity is increased by hypofractionated irradiation
por: Kötter, Bernhard, et al.
Publicado: (2015)

Regulation of LncRNAs in Melanoma and Their Functional Roles in the Metastatic Process
por: Melixetian, Marine, et al.
Publicado: (2022)

12 × 6 Gy stereotactic radiotherapy for lung tumors. Is there a difference in response between lung metastases and primary bronchial carcinoma?
por: Lubgan, Dorota, et al.
Publicado: (2021)

Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy
por: Dai, Jie, et al.
Publicado: (2023)

Construction of a Novel Prognostic Signature in Lung Adenocarcinoma Based on Necroptosis-Related lncRNAs
por: Diao, Xiayao, et al.
Publicado: (2022)

LncRNAs Expression Signatures of Renal Clear Cell Carcinoma Revealed by Microarray
por: Yu, Gan, et al.
Publicado: (2012)

Prospective Evaluation of CD45RA+/CCR7- Effector Memory T (T(EMRA)) Cell Subsets in Patients with Primary and Secondary Brain Tumors during Radiotherapy of the Brain within the Scope of the Prospective Glio-CMV-01 Clinical Trial
por: Scheer, Ilka, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ifl1pogn5jgbr6ompdp2266nfh