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Biochemical profiling of anti-HIV prodrug Elsulfavirine (Elpida(®)) and its active form VM1500A against a panel of twelve human carbonic anhydrase isoforms

The non-nucleoside reverse transcriptase inhibitor VM1500A is approved for the treatment of HIV/AIDS in its N-acyl sulphonamide prodrug form elsulfavirine (Elpida(®)). Biochemical profiling against twelve human carbonic anhydrase (CA, EC 4.2.1.1) isoforms showed that while elsulfavirine was a weak i...

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Detalles Bibliográficos
Autores principales:	Supuran, Claudiu T., Nocentini, Alessio, Yakubova, Elena, Savchuk, Nikolay, Kalinin, Stanislav, Krasavin, Mikhail
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143618/ https://www.ncbi.nlm.nih.gov/pubmed/34000969 http://dx.doi.org/10.1080/14756366.2021.1927007

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