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Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression

OBJECTIVE: Peritoneal fibrosis (PF) ultimately causes ultrafiltration failure and peritoneal dialysis (PD) termination, but there are few effective therapies for it. Core fucosylation, which is catalyzed by α1,6-fucosyltransferase (Fut8) in mammals, may play a crucial role in PF development. This st...

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Detalles Bibliográficos
Autores principales:	Yu, Changqing, Yang, Ning, Wang, Weidong, Du, Xiangning, Tang, Qingzhu, Lin, Hongli, Li, Longkai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Laboratory Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143636/ https://www.ncbi.nlm.nih.gov/pubmed/33993842 http://dx.doi.org/10.1080/0886022X.2021.1918557

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