Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents

Kir2.1, a strong inward rectifier potassium channel encoded by the KCNJ2 gene, is a key regulator of the resting membrane potential of the cardiomyocyte and plays an important role in controlling ventricular excitation and action potential duration in the human heart. Mutations in KCNJ2 result in in...

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Detalles Bibliográficos
Autores principales: Park, Sung-Soo, Ponce-Balbuena, Daniela, Kuick, Rork, Guerrero-Serna, Guadalupe, Yoon, Justin, Mellacheruvu, Dattatreya, Conlon, Kevin P., Basrur, Venkatesha, Nesvizhskii, Alexey I., Jalife, José, Rual, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143648/
https://www.ncbi.nlm.nih.gov/pubmed/32541000
http://dx.doi.org/10.1074/mcp.RA120.002071

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