PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets

OBJECTIVE(S): Cancer stem cells (CSCs) have powerful self-renewal ability and tumor recurrence. Pancreatic ductal adenocarcinoma is a malignancy with high mortality rate and ˃5% survival. Silybin has anticancer and hepatoprotective properties. We loaded silybin in PEG400-OA (SPNs) and evaluated its...

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Detalles Bibliográficos
Autores principales: Khakinezhad Tehrani, Fatemeh, Ranji, Najmeh, Kouhkan, Fatemeh, Hosseinzadeh, Simzar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143704/
https://www.ncbi.nlm.nih.gov/pubmed/34094034
http://dx.doi.org/10.22038/ijbms.2021.54001.12136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143704/
https://www.ncbi.nlm.nih.gov/pubmed/34094034
http://dx.doi.org/10.22038/ijbms.2021.54001.12136

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