A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management

There is a need for understanding and establishment of the most appropriate testing algorithm for COVID-19 diagnosis in asymptomatic high-risk groups. Here, we present a retrospective analysis of RT-PCR results obtained from 412 cases tested negative for coronavirus disease 2019 (COVID-19) by rapid...

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Autores principales: Munne, Kiran, Bhanothu, Venkanna, Mayekar, Anjali, Birje, Shantanu, Bhor, Vikrant, Patel, Vainav, Mahale, Smita D., Pande, Shailesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143916/
https://www.ncbi.nlm.nih.gov/pubmed/34045083
http://dx.doi.org/10.1016/j.ijmmb.2021.05.006
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author Munne, Kiran
Bhanothu, Venkanna
Mayekar, Anjali
Birje, Shantanu
Bhor, Vikrant
Patel, Vainav
Mahale, Smita D.
Pande, Shailesh S.
author_facet Munne, Kiran
Bhanothu, Venkanna
Mayekar, Anjali
Birje, Shantanu
Bhor, Vikrant
Patel, Vainav
Mahale, Smita D.
Pande, Shailesh S.
author_sort Munne, Kiran
collection PubMed
description There is a need for understanding and establishment of the most appropriate testing algorithm for COVID-19 diagnosis in asymptomatic high-risk groups. Here, we present a retrospective analysis of RT-PCR results obtained from 412 cases tested negative for coronavirus disease 2019 (COVID-19) by rapid antigen testing method. Among 178 (43.2%) asymptomatic individuals, 44.9% of the high risk contacts, 12.2% of police custody individuals, 22.22% of the pregnant women and 33.33% of individuals hospitalised for preoperative or other medical conditions showed RT-PCR positivity. Our results suggest a need for focussed and intensive (multi-modality) testing in groups at high risk for SARS-CoV-2 infection.
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spelling pubmed-81439162021-05-25 A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management Munne, Kiran Bhanothu, Venkanna Mayekar, Anjali Birje, Shantanu Bhor, Vikrant Patel, Vainav Mahale, Smita D. Pande, Shailesh S. Indian J Med Microbiol Brief Communication There is a need for understanding and establishment of the most appropriate testing algorithm for COVID-19 diagnosis in asymptomatic high-risk groups. Here, we present a retrospective analysis of RT-PCR results obtained from 412 cases tested negative for coronavirus disease 2019 (COVID-19) by rapid antigen testing method. Among 178 (43.2%) asymptomatic individuals, 44.9% of the high risk contacts, 12.2% of police custody individuals, 22.22% of the pregnant women and 33.33% of individuals hospitalised for preoperative or other medical conditions showed RT-PCR positivity. Our results suggest a need for focussed and intensive (multi-modality) testing in groups at high risk for SARS-CoV-2 infection. Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2021 2021-05-25 /pmc/articles/PMC8143916/ /pubmed/34045083 http://dx.doi.org/10.1016/j.ijmmb.2021.05.006 Text en © 2021 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Communication
Munne, Kiran
Bhanothu, Venkanna
Mayekar, Anjali
Birje, Shantanu
Bhor, Vikrant
Patel, Vainav
Mahale, Smita D.
Pande, Shailesh S.
A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management
title A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management
title_full A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management
title_fullStr A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management
title_full_unstemmed A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management
title_short A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management
title_sort retrospective analysis of covid-19 diagnosis results obtained by rapid antigen tests and rt-pcr: implications for disease management
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143916/
https://www.ncbi.nlm.nih.gov/pubmed/34045083
http://dx.doi.org/10.1016/j.ijmmb.2021.05.006
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