OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics

Several OPRD1 intronic variants were associated with opioid addiction (OD) in a population-specific manner. This follow-up study aims to further characterize the OPRD1 haplotype pattern of the risk variants in different populations and apply in silico analysis to identify potential causal variants....

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Detalles Bibliográficos
Autores principales: Levran, Orna, Randesi, Matthew, Adelson, Miriam, Kreek, Mary Jeanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144180/
https://www.ncbi.nlm.nih.gov/pubmed/34031368
http://dx.doi.org/10.1038/s41398-021-01439-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144180/
https://www.ncbi.nlm.nih.gov/pubmed/34031368
http://dx.doi.org/10.1038/s41398-021-01439-y

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