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The ACE2-Ang-(1‑7)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Mediated NF-кb and MAPK Pathways

PURPOSE: Angiotensin 1–7 [Ang-(1-7)] has been identified as an important anti-inflammatory and anti-fibrotic factor. This study determined how the ACE2-Ang-(1-7)-Mas axis affected M1/M2 macrophage polarization and thus contributed to anti-inflammatory processes in the cecal ligation and puncture (CL...

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Detalles Bibliográficos
Autores principales:	Pan, Hang, Huang, Wenhan, Wang, Zhongjie, Ren, Feifeng, Luo, Lei, Zhou, Jun, Tian, Mengxue, Tang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144186/ https://www.ncbi.nlm.nih.gov/pubmed/34045880 http://dx.doi.org/10.2147/JIR.S307801

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