Cargando…

Causal Effects of Body Mass Index on Airflow Obstruction and Forced Mid-Expiratory Flow: A Mendelian Randomization Study Taking Interactions and Age-Specific Instruments Into Consideration Toward a Life Course Perspective

Obesity has complex links to respiratory health. Mendelian randomization (MR) enables assessment of causality of body mass index (BMI) effects on airflow obstruction and mid-expiratory flow. In the adult SAPALDIA cohort, recruiting 9,651 population-representative samples aged 18–60 years at baseline...

Descripción completa

Detalles Bibliográficos
Autores principales:	Probst-Hensch, Nicole, Jeong, Ayoung, Stolz, Daiana, Pons, Marco, Soccal, Paola M., Bettschart, Robert, Jarvis, Deborah, Holloway, John W., Kronenberg, Florian, Imboden, Medea, Schindler, Christian, Lovison, Gianfranco F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Public Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144328/ https://www.ncbi.nlm.nih.gov/pubmed/34046380 http://dx.doi.org/10.3389/fpubh.2021.584955

Ejemplares similares

DNA Methylation in Inflammatory Pathways Modifies the Association between BMI and Adult-Onset Non-Atopic Asthma
por: Jeong, Ayoung, et al.
Publicado: (2019)

Perceived built environment, health-related quality of life and health care utilization
por: Cerletti, Paco, et al.
Publicado: (2021)

SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts
por: Beckmeyer-Borowko, Anna, et al.
Publicado: (2018)

A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM(10) exposure and diabetes
por: Eze, Ikenna C., et al.
Publicado: (2016)

The mediating effect of immune markers on the association between ambient air pollution and adult-onset asthma
por: Mostafavi, Nahid, et al.
Publicado: (2019)

Modification of the Association between PM(10) and Lung Function Decline by Cadherin 13 Polymorphisms in the SAPALDIA Cohort: A Genome-Wide Interaction Analysis
por: Imboden, Medea, et al.
Publicado: (2014)

Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study
por: Amaral, André F. S., et al.
Publicado: (2020)

The modifying role of physical activity in the cross-sectional and longitudinal association of health-related quality of life with physiological functioning-based latent classes and metabolic syndrome
por: Cerletti, Paco, et al.
Publicado: (2020)

Biobanking across the phenome - at the center of chronic disease research
por: Imboden, Medea, et al.
Publicado: (2013)

Depression and cardiovascular disease are not linked by high blood pressure: findings from the SAPALDIA cohort
por: Obas, Katrina A., et al.
Publicado: (2022)

Depression trajectories during the COVID-19 pandemic in the high-quality health care setting of Switzerland: the COVCO-Basel cohort
por: Probst-Hensch, N., et al.
Publicado: (2023)

Association of adult lung function with accelerated biological aging
por: Rezwan, Faisal I., et al.
Publicado: (2020)

Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study
por: Eze, Ikenna C., et al.
Publicado: (2020)

Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study
por: Accordini, Simone, et al.
Publicado: (2020)

Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies
por: Machin, Matthew, et al.
Publicado: (2017)

Modifying Effect of a Common Polymorphism in the Interleukin-6 Promoter on the Relationship between Long-Term Exposure to Traffic-Related Particulate Matter and Heart Rate Variability
por: Adam, Martin, et al.
Publicado: (2014)

Different Genes Interact with Particulate Matter and Tobacco Smoke Exposure in Affecting Lung Function Decline in the General Population
por: Curjuric, Ivan, et al.
Publicado: (2012)

Peak Expiratory Flow Rate Underestimates Severity of Airflow Obstruction in Acute Asthma
por: Choi, Inseon S., et al.
Publicado: (2002)

A laboratory study of the expiratory airflow and particle dispersion in the stratified indoor environment
por: Liu, Fan, et al.
Publicado: (2020)

Comparative evaluation of expiratory airflow limitation between patients with COPD and BE using IOS
por: dos Santos, Daniele Oliveira, et al.
Publicado: (2021)

Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study
por: Imboden, Medea, et al.
Publicado: (2007)

Assessment of Airway Closure and Expiratory Airflow Limitation to Set Positive End-Expiratory Pressure in Morbidly Obese Patients with Acute Respiratory Distress Syndrome
por: Mezidi, Mehdi, et al.
Publicado: (2021)

Decreased PM(10) Exposure Attenuates Age-Related Lung Function Decline: Genetic Variants in p53, p21, and CCND1 Modify This Effect
por: Imboden, Medea, et al.
Publicado: (2009)

Long-Term Exposure to Ambient Air Pollution and Metabolic Syndrome in Adults
por: Eze, Ikenna C., et al.
Publicado: (2015)

Repurposing catheter ablation work-up to detect expiratory airflow limitation in patients with atrial fibrillation()
por: Hereijgers, Maartje J.M., et al.
Publicado: (2023)

Association between tuberculosis, diabetes and 25 hydroxyvitamin D in Tanzania: a longitudinal case control study
por: Boillat-Blanco, Noémie, et al.
Publicado: (2016)

Environmental tobacco smoke exposure and diabetes in adult never-smokers
por: Eze, Ikenna C, et al.
Publicado: (2014)

Influence of two-dimensional expiratory airflow variations on respiratory particle propagation during pronunciation of the fricative [f]
por: Mofakham, Amir A., et al.
Publicado: (2023)

Extended use of preprocedural data to detect expiratory airflow limitation in patients with atrial fibrillation scheduled for ablation
por: Hereijgers, M J M, et al.
Publicado: (2023)

SERPINA1 PiZ and PiS Heterozygotes and Lung Function Decline in the SAPALDIA Cohort
por: Thun, Gian-Andri, et al.
Publicado: (2012)

Circulating alpha1-antitrypsin in the general population: Determinants and association with lung function
por: Senn, Oliver, et al.
Publicado: (2008)

Glutathione S-Transferase Polymorphisms, Passive Smoking, Obesity, and Heart Rate Variability in Nonsmokers
por: Probst-Hensch, Nicole M., et al.
Publicado: (2008)

Higher BMI is associated with higher expiratory airflow normalised for lung volume (FEF25–75/FVC) in COPD
por: Abston, Eric, et al.
Publicado: (2017)

Long-term expiratory airflow of infants born moderate-late preterm: A systematic review and meta-analysis
por: Du Berry, Cassidy, et al.
Publicado: (2022)

Reply to Mezidi et al.: Assessment of Airway Closure and Expiratory Airflow Limitation to Set Positive End-Expiratory Pressure in Morbidly Obese Patients with Acute Respiratory Distress Syndrome
por: Balakrishna, Aditi, et al.
Publicado: (2021)

Concave Pattern of a Maximal Expiratory Flow-Volume Curve: A Sign of Airflow Limitation in Adult Bronchial Asthma
por: Ohwada, Akihiko, et al.
Publicado: (2012)

3D-measurement of tracheobronchial angles on inspiratory and expiratory chest CT in COPD: respiratory changes and correlation with airflow limitation
por: Onoe, Rintaro, et al.
Publicado: (2018)

Associations between domains of physical activity, sitting time, and different measures of overweight and obesity
por: Wanner, Miriam, et al.
Publicado: (2016)

Variability of the Human Serum Metabolome over 3 Months in the EXPOsOMICS Personal Exposure Monitoring Study
por: Oosterwegel, Max J., et al.
Publicado: (2023)

Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study
por: Eze, Ikenna C, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_grdfa90g4fe71jgvcn5iu5h6lb