Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity

Cardiotoxicity in the late phase after anthracycline drugs administration remains to be defined. Of the 44 patients who received anthracycline treatment, 7 were found to have cancer therapeutics–related cardiac dysfunction (CTRCD). The global longitudinal strain determined by echocardiography and my...

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Autores principales: Egashira, Koichi, Sueta, Daisuke, Tomiguchi, Mai, Kidoh, Masafumi, Oda, Seitaro, Usuku, Hiroki, Hidaka, Kaori, Goto-Yamaguchi, Lisa, Sueta, Aiko, Komorita, Takashi, Takae, Masafumi, Oike, Fumi, Fujisue, Koichiro, Yamamoto, Eiichiro, Hanatani, Shinsuke, Takashio, Seiji, Arima, Yuichiro, Araki, Satoshi, Kaikita, Koichi, Matsushita, Kenichi, Yamamoto, Yutaka, Hirai, Toshinori, Tsujita, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144341/
https://www.ncbi.nlm.nih.gov/pubmed/34041357
http://dx.doi.org/10.1016/j.ijcha.2021.100797
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author Egashira, Koichi
Sueta, Daisuke
Tomiguchi, Mai
Kidoh, Masafumi
Oda, Seitaro
Usuku, Hiroki
Hidaka, Kaori
Goto-Yamaguchi, Lisa
Sueta, Aiko
Komorita, Takashi
Takae, Masafumi
Oike, Fumi
Fujisue, Koichiro
Yamamoto, Eiichiro
Hanatani, Shinsuke
Takashio, Seiji
Arima, Yuichiro
Araki, Satoshi
Kaikita, Koichi
Matsushita, Kenichi
Yamamoto, Yutaka
Hirai, Toshinori
Tsujita, Kenichi
author_facet Egashira, Koichi
Sueta, Daisuke
Tomiguchi, Mai
Kidoh, Masafumi
Oda, Seitaro
Usuku, Hiroki
Hidaka, Kaori
Goto-Yamaguchi, Lisa
Sueta, Aiko
Komorita, Takashi
Takae, Masafumi
Oike, Fumi
Fujisue, Koichiro
Yamamoto, Eiichiro
Hanatani, Shinsuke
Takashio, Seiji
Arima, Yuichiro
Araki, Satoshi
Kaikita, Koichi
Matsushita, Kenichi
Yamamoto, Yutaka
Hirai, Toshinori
Tsujita, Kenichi
author_sort Egashira, Koichi
collection PubMed
description Cardiotoxicity in the late phase after anthracycline drugs administration remains to be defined. Of the 44 patients who received anthracycline treatment, 7 were found to have cancer therapeutics–related cardiac dysfunction (CTRCD). The global longitudinal strain determined by echocardiography and myocardial extracellular volume fraction (ECV) determined by cardiac computed tomography (CCT) of the CTRCD(+) group were significantly higher than those of the control group and CTRCD(-) group, whereas there were no significant differences between the control and CTRCD(-) groups. Our findings indicated that CCT may be a tool comparable to echocardiography, indicating the effective evaluation of CTRCD by CCT.
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spelling pubmed-81443412021-05-25 Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity Egashira, Koichi Sueta, Daisuke Tomiguchi, Mai Kidoh, Masafumi Oda, Seitaro Usuku, Hiroki Hidaka, Kaori Goto-Yamaguchi, Lisa Sueta, Aiko Komorita, Takashi Takae, Masafumi Oike, Fumi Fujisue, Koichiro Yamamoto, Eiichiro Hanatani, Shinsuke Takashio, Seiji Arima, Yuichiro Araki, Satoshi Kaikita, Koichi Matsushita, Kenichi Yamamoto, Yutaka Hirai, Toshinori Tsujita, Kenichi Int J Cardiol Heart Vasc Original Paper Cardiotoxicity in the late phase after anthracycline drugs administration remains to be defined. Of the 44 patients who received anthracycline treatment, 7 were found to have cancer therapeutics–related cardiac dysfunction (CTRCD). The global longitudinal strain determined by echocardiography and myocardial extracellular volume fraction (ECV) determined by cardiac computed tomography (CCT) of the CTRCD(+) group were significantly higher than those of the control group and CTRCD(-) group, whereas there were no significant differences between the control and CTRCD(-) groups. Our findings indicated that CCT may be a tool comparable to echocardiography, indicating the effective evaluation of CTRCD by CCT. Elsevier 2021-05-18 /pmc/articles/PMC8144341/ /pubmed/34041357 http://dx.doi.org/10.1016/j.ijcha.2021.100797 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Paper
Egashira, Koichi
Sueta, Daisuke
Tomiguchi, Mai
Kidoh, Masafumi
Oda, Seitaro
Usuku, Hiroki
Hidaka, Kaori
Goto-Yamaguchi, Lisa
Sueta, Aiko
Komorita, Takashi
Takae, Masafumi
Oike, Fumi
Fujisue, Koichiro
Yamamoto, Eiichiro
Hanatani, Shinsuke
Takashio, Seiji
Arima, Yuichiro
Araki, Satoshi
Kaikita, Koichi
Matsushita, Kenichi
Yamamoto, Yutaka
Hirai, Toshinori
Tsujita, Kenichi
Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity
title Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity
title_full Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity
title_fullStr Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity
title_full_unstemmed Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity
title_short Cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity
title_sort cardiac computed tomography-derived extracellular volume fraction in late anthracycline-induced cardiotoxicity
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144341/
https://www.ncbi.nlm.nih.gov/pubmed/34041357
http://dx.doi.org/10.1016/j.ijcha.2021.100797
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