IGF1R and Src inhibition induce synergistic cytotoxicity in HNSCC through inhibition of FAK

Head and neck cancer is the sixth most common cancer worldwide with a 5-year survival of only 65%. Targeting compensatory signaling pathways may improve therapeutic responses and combat resistance. Utilizing reverse phase protein arrays (RPPA) to assess the proteome and explore mechanisms of synergi...

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Detalles Bibliográficos
Autores principales: Lehman, Christine E., Spencer, Adam, Hall, Sarah, Shaw, Jeremy J. P., Wulfkuhle, Julia, Petricoin, Emanuel F., Bekiranov, Stefan, Jameson, Mark J., Gioeli, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144381/
https://www.ncbi.nlm.nih.gov/pubmed/34031486
http://dx.doi.org/10.1038/s41598-021-90289-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144381/
https://www.ncbi.nlm.nih.gov/pubmed/34031486
http://dx.doi.org/10.1038/s41598-021-90289-1

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