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Evaluation of LDL goal achievement in statin consumption, south east of Iran
Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examine...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144405/ https://www.ncbi.nlm.nih.gov/pubmed/34031484 http://dx.doi.org/10.1038/s41598-021-90228-0 |
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author | Aghasizadeh, Malihe Bizhaem, Saeede Khosravi Baniasadi, Mahin Khazdair, Mohammad Reza Kazemi, Toba |
author_facet | Aghasizadeh, Malihe Bizhaem, Saeede Khosravi Baniasadi, Mahin Khazdair, Mohammad Reza Kazemi, Toba |
author_sort | Aghasizadeh, Malihe |
collection | PubMed |
description | Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examined LDL-C values and the proportion reaching targets according to the American Association of Clinical Endocrinologists guideline. Three patterns of statin use (high/moderate/low-intensity statin therapy) in all patients were examined and attainments of LDL-C goal in cardiovascular risk groups have been demonstrated. Over half the populations (57.6%) were in the very-high CVD risk group. The results showed that the proportion of patients meeting total LDL-C goal values according to the guidelines was 43.4%. The frequency of patient had achievement LDL goal lower in high-intensity pattern (N = 13, 2.3%), compared with moderate (N = 496, 86.1%) and low-intensity patterns (N = 67, 11.6%). In general, LDL-C goal achievement was greatest with moderate-intensity statin use. LDL-C reduction after statin consumption was estimated about one-third of the studied population. It seems likely that the achievement of a therapeutic target for serum lipids such as LDL-C improved is far more cost-effective and would be able to reach the target LDL as well changing the type and intensity of statins. |
format | Online Article Text |
id | pubmed-8144405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-81444052021-05-25 Evaluation of LDL goal achievement in statin consumption, south east of Iran Aghasizadeh, Malihe Bizhaem, Saeede Khosravi Baniasadi, Mahin Khazdair, Mohammad Reza Kazemi, Toba Sci Rep Article Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examined LDL-C values and the proportion reaching targets according to the American Association of Clinical Endocrinologists guideline. Three patterns of statin use (high/moderate/low-intensity statin therapy) in all patients were examined and attainments of LDL-C goal in cardiovascular risk groups have been demonstrated. Over half the populations (57.6%) were in the very-high CVD risk group. The results showed that the proportion of patients meeting total LDL-C goal values according to the guidelines was 43.4%. The frequency of patient had achievement LDL goal lower in high-intensity pattern (N = 13, 2.3%), compared with moderate (N = 496, 86.1%) and low-intensity patterns (N = 67, 11.6%). In general, LDL-C goal achievement was greatest with moderate-intensity statin use. LDL-C reduction after statin consumption was estimated about one-third of the studied population. It seems likely that the achievement of a therapeutic target for serum lipids such as LDL-C improved is far more cost-effective and would be able to reach the target LDL as well changing the type and intensity of statins. Nature Publishing Group UK 2021-05-24 /pmc/articles/PMC8144405/ /pubmed/34031484 http://dx.doi.org/10.1038/s41598-021-90228-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Aghasizadeh, Malihe Bizhaem, Saeede Khosravi Baniasadi, Mahin Khazdair, Mohammad Reza Kazemi, Toba Evaluation of LDL goal achievement in statin consumption, south east of Iran |
title | Evaluation of LDL goal achievement in statin consumption, south east of Iran |
title_full | Evaluation of LDL goal achievement in statin consumption, south east of Iran |
title_fullStr | Evaluation of LDL goal achievement in statin consumption, south east of Iran |
title_full_unstemmed | Evaluation of LDL goal achievement in statin consumption, south east of Iran |
title_short | Evaluation of LDL goal achievement in statin consumption, south east of Iran |
title_sort | evaluation of ldl goal achievement in statin consumption, south east of iran |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144405/ https://www.ncbi.nlm.nih.gov/pubmed/34031484 http://dx.doi.org/10.1038/s41598-021-90228-0 |
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