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Evaluation of LDL goal achievement in statin consumption, south east of Iran

Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examine...

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Autores principales: Aghasizadeh, Malihe, Bizhaem, Saeede Khosravi, Baniasadi, Mahin, Khazdair, Mohammad Reza, Kazemi, Toba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144405/
https://www.ncbi.nlm.nih.gov/pubmed/34031484
http://dx.doi.org/10.1038/s41598-021-90228-0
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author Aghasizadeh, Malihe
Bizhaem, Saeede Khosravi
Baniasadi, Mahin
Khazdair, Mohammad Reza
Kazemi, Toba
author_facet Aghasizadeh, Malihe
Bizhaem, Saeede Khosravi
Baniasadi, Mahin
Khazdair, Mohammad Reza
Kazemi, Toba
author_sort Aghasizadeh, Malihe
collection PubMed
description Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examined LDL-C values and the proportion reaching targets according to the American Association of Clinical Endocrinologists guideline. Three patterns of statin use (high/moderate/low-intensity statin therapy) in all patients were examined and attainments of LDL-C goal in cardiovascular risk groups have been demonstrated. Over half the populations (57.6%) were in the very-high CVD risk group. The results showed that the proportion of patients meeting total LDL-C goal values according to the guidelines was 43.4%. The frequency of patient had achievement LDL goal lower in high-intensity pattern (N = 13, 2.3%), compared with moderate (N = 496, 86.1%) and low-intensity patterns (N = 67, 11.6%). In general, LDL-C goal achievement was greatest with moderate-intensity statin use. LDL-C reduction after statin consumption was estimated about one-third of the studied population. It seems likely that the achievement of a therapeutic target for serum lipids such as LDL-C improved is far more cost-effective and would be able to reach the target LDL as well changing the type and intensity of statins.
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spelling pubmed-81444052021-05-25 Evaluation of LDL goal achievement in statin consumption, south east of Iran Aghasizadeh, Malihe Bizhaem, Saeede Khosravi Baniasadi, Mahin Khazdair, Mohammad Reza Kazemi, Toba Sci Rep Article Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examined LDL-C values and the proportion reaching targets according to the American Association of Clinical Endocrinologists guideline. Three patterns of statin use (high/moderate/low-intensity statin therapy) in all patients were examined and attainments of LDL-C goal in cardiovascular risk groups have been demonstrated. Over half the populations (57.6%) were in the very-high CVD risk group. The results showed that the proportion of patients meeting total LDL-C goal values according to the guidelines was 43.4%. The frequency of patient had achievement LDL goal lower in high-intensity pattern (N = 13, 2.3%), compared with moderate (N = 496, 86.1%) and low-intensity patterns (N = 67, 11.6%). In general, LDL-C goal achievement was greatest with moderate-intensity statin use. LDL-C reduction after statin consumption was estimated about one-third of the studied population. It seems likely that the achievement of a therapeutic target for serum lipids such as LDL-C improved is far more cost-effective and would be able to reach the target LDL as well changing the type and intensity of statins. Nature Publishing Group UK 2021-05-24 /pmc/articles/PMC8144405/ /pubmed/34031484 http://dx.doi.org/10.1038/s41598-021-90228-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Aghasizadeh, Malihe
Bizhaem, Saeede Khosravi
Baniasadi, Mahin
Khazdair, Mohammad Reza
Kazemi, Toba
Evaluation of LDL goal achievement in statin consumption, south east of Iran
title Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_full Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_fullStr Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_full_unstemmed Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_short Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_sort evaluation of ldl goal achievement in statin consumption, south east of iran
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144405/
https://www.ncbi.nlm.nih.gov/pubmed/34031484
http://dx.doi.org/10.1038/s41598-021-90228-0
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