Cargando…

Cannabidiol Modulates Mitochondrial Redox and Dynamics in MCF7 Cancer Cells: A Study Using Fluorescence Lifetime Imaging Microscopy of NAD(P)H

The cannabinoid, cannabidiol (CBD), is part of the plant's natural defense system that when given to animals has many useful medicinal properties, including activity against cancer cells, modulation of the immune system, and efficacy in epilepsy. Although there is no consensus on its precise mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mould, Rhys Richard, Botchway, Stanley W., Parkinson, James R. C., Thomas, Elizabeth Louise, Guy, Geoffrey W, Bell, Jimmy D., Nunn, Alistair V. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144465/ https://www.ncbi.nlm.nih.gov/pubmed/34046425 http://dx.doi.org/10.3389/fmolb.2021.630107

Ejemplares similares

Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
por: Kosgodage, Uchini S., et al.
Publicado: (2018)

From sunscreens to medicines: Can a dissipation hypothesis explain the beneficial aspects of many plant compounds?
por: Nunn, Alistair V.W., et al.
Publicado: (2020)

SARS-CoV-2 and EBV; the cost of a second mitochondrial “whammy”?
por: Nunn, Alistair V.W., et al.
Publicado: (2021)

Combining Multicolor FISH with Fluorescence Lifetime Imaging for Chromosomal Identification and Chromosomal Sub Structure Investigation
por: Bhartiya, Archana, et al.
Publicado: (2021)

Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells()()
por: Kosgodage, Uchini S., et al.
Publicado: (2018)

Non-chemical signalling between mitochondria
por: Mould, Rhys R., et al.
Publicado: (2023)

SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing
por: Nunn, Alistair V. W., et al.
Publicado: (2020)

Cannabidiol Is a Novel Modulator of Bacterial Membrane Vesicles
por: Kosgodage, Uchini S., et al.
Publicado: (2019)

Acetate Induces Growth Arrest in Colon Cancer Cells Through Modulation of Mitochondrial Function
por: Sahuri-Arisoylu, Meliz, et al.
Publicado: (2021)

The intelligence paradox; will ET get the metabolic syndrome? Lessons from and for Earth
por: Nunn, Alistair V W, et al.
Publicado: (2014)

The quantum mitochondrion and optimal health
por: Nunn, Alistair V.W., et al.
Publicado: (2016)

Bioelectric Fields at the Beginnings of Life
por: Nunn, Alistair V.W., et al.
Publicado: (2022)

Informing the Cannabis Conjecture: From Life’s Beginnings to Mitochondria, Membranes and the Electrome—A Review
por: Nunn, Alistair V. W., et al.
Publicado: (2023)

Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?
por: Nunn, Alistair VW, et al.
Publicado: (2009)

Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function
por: Nunn, Alistair, et al.
Publicado: (2012)

Understanding Long COVID; Mitochondrial Health and Adaptation—Old Pathways, New Problems
por: Nunn, Alistair V. W., et al.
Publicado: (2022)

Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle
por: Nunn, Alistair V, et al.
Publicado: (2010)

NAD(+) Metabolism, Metabolic Stress, and Infection
por: Groth, Benjamin, et al.
Publicado: (2021)

NADH Fluorescence Lifetime Imaging Microscopy Reveals Selective Mitochondrial Dysfunction in Neurons Overexpressing Alzheimer’s Disease–Related Proteins
por: Niederschweiberer, Moritz A., et al.
Publicado: (2021)

Fluorescence spectroscopy and microscopy as tools for monitoring redox transformations of uranium in biological systems
por: Jones, Debbie L., et al.
Publicado: (2015)

A Combined Acceptor Photobleaching and Donor Fluorescence Lifetime Imaging Microscopy Approach to Analyze Multi-Protein Interactions in Living Cells
por: Eckenstaler, Robert, et al.
Publicado: (2021)

NAD(+) Degrading Enzymes, Evidence for Roles During Infection
por: Tan, Arnold, et al.
Publicado: (2021)

Oxygen Mapping of Melanoma Spheroids using Small Molecule Platinum Probe and Phosphorescence Lifetime Imaging Microscopy
por: Raza, Ahtasham, et al.
Publicado: (2017)

Editorial: NAD+ metabolism as a novel target against infection–Volume II
por: Balducci, Enrico, et al.
Publicado: (2022)

A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity
por: Hopkins, Eleanor L., et al.
Publicado: (2021)

Two NAD-linked redox shuttles maintain the peroxisomal redox balance in Saccharomyces cerevisiae
por: Al-Saryi, Nadal A., et al.
Publicado: (2017)

Bacterial hemerythrin domain-containing oxygen and redox sensors: Versatile roles for oxygen and redox signaling
por: Kitanishi, Kenichi
Publicado: (2022)

Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells
por: Yang, Wenqian, et al.
Publicado: (2022)

Fluorescent naphthalimide boronates as theranostics: structural investigations, confocal fluorescence and multiphoton fluorescence lifetime imaging microscopy in living cells
por: Green, Megan J., et al.
Publicado: (2023)

Rapamycin maintains NAD(+)/NADH redox homeostasis in muscle cells
por: Zhang, Zhigang, et al.
Publicado: (2020)

Peroxisomal NAD(H) Homeostasis in the Yeast Debaryomyces hansenii Depends on Two Redox Shuttles and the NAD(+) Carrier, Pmp47
por: Turkolmez, Selva, et al.
Publicado: (2023)

Methionine Redox Homeostasis in Protein Quality Control
por: Aussel, Laurent, et al.
Publicado: (2021)

Label-free characterization of single extracellular vesicles using two-photon fluorescence lifetime imaging microscopy of NAD(P)H
por: Sorrells, Janet E., et al.
Publicado: (2021)

Simultaneous NAD(P)H and FAD fluorescence lifetime microscopy of long UVA–induced metabolic stress in reconstructed human skin
por: Ung, Thi Phuong Lien, et al.
Publicado: (2021)

Predicting Drosha and Dicer Cleavage Sites with DeepMirCut
por: Bell, Jimmy, et al.
Publicado: (2022)

Single Domain Antibodies Targeting Receptor Binding Pockets of NadA Restrain Adhesion of Neisseria meningitidis to Human Brain Microvascular Endothelial Cells
por: Kulkarni, Amod, et al.
Publicado: (2020)

The Identification of a Novel Calcium-Dependent Link Between NAD(+) and Glucose Deprivation-Induced Increases in Protein O-GlcNAcylation and ER Stress
por: Zou, Luyun, et al.
Publicado: (2021)

Redox Switches in Noise-Induced Cardiovascular and Neuronal Dysregulation
por: Frenis, Katie, et al.
Publicado: (2021)

The Central Role of Redox-Regulated Switch Proteins in Bacteria
por: Fassler, Rosi, et al.
Publicado: (2021)

Mitochondrial NAD(+)/NADH Redox State and Diabetic Cardiomyopathy
por: Berthiaume, Jessica M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mrbk59fspmvo50u1kotfkm7rqu