Cargando…

The Role of RNA Methyltransferase METTL3 in Hepatocellular Carcinoma: Results and Perspectives

Hepatocellular carcinoma (HCC) is the 6th most prevalent cancer and the 4th leading cause of cancer-related death worldwide. Mechanisms explaining the carcinogenesis of HCC are not clear yet. In recent years, rapid development of N(6)-methyladenosine (m6A) modification provides a fresh approach to d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Fan, Lin, Xin-Rong, Hao, Li-Ping, Chu, Xiao-Yuan, Wan, Hai-Jun, Wang, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144501/ https://www.ncbi.nlm.nih.gov/pubmed/34046411 http://dx.doi.org/10.3389/fcell.2021.674919

Ejemplares similares

m7G Methyltransferase METTL1 Promotes Post-ischemic Angiogenesis via Promoting VEGFA mRNA Translation
por: Zhao, Yongchao, et al.
Publicado: (2021)

The Critical Role of Ferroptosis in Hepatocellular Carcinoma
por: Pan, Fan, et al.
Publicado: (2022)

The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1
por: Shi, Yue, et al.
Publicado: (2021)

The RNA Methyltransferase METTL3 Promotes Endothelial Progenitor Cell Angiogenesis in Mandibular Distraction Osteogenesis via the PI3K/AKT Pathway
por: Jiang, Weidong, et al.
Publicado: (2021)

METTL3-Mediated N6-Methyladenosine Modification Is Involved in the Dysregulation of NRIP1 Expression in Down Syndrome
por: Shi, Weili, et al.
Publicado: (2021)

N6-Methyladenosine Methyltransferase METTL3 Promotes Angiogenesis and Atherosclerosis by Upregulating the JAK2/STAT3 Pathway via m6A Reader IGF2BP1
por: Dong, Guo, et al.
Publicado: (2021)

Fine-tuning of regulatory T cells is indispensable for the metabolic steatosis-related hepatocellular carcinoma: A review
por: Riaz, Farooq, et al.
Publicado: (2022)

Deficiency of Mettl3 in Bladder Cancer Stem Cells Inhibits Bladder Cancer Progression and Angiogenesis
por: Wang, Ganping, et al.
Publicado: (2021)

Corrigendum: Deficiency of Mettl3 in Bladder Cancer Stem Cells Inhibits Bladder Cancer Progression and Angiogenesis
por: Wang, Ganping, et al.
Publicado: (2021)

Mettl14 Attenuates Cardiac Ischemia/Reperfusion Injury by Regulating Wnt1/β-Catenin Signaling Pathway
por: Pang, Ping, et al.
Publicado: (2021)

Integrated Analysis Reveals the Gut Microbial Metabolite TMAO Promotes Inflammatory Hepatocellular Carcinoma by Upregulating POSTN
por: Wu, Yonglin, et al.
Publicado: (2022)

Identification of novel lactate metabolism signatures and molecular subtypes for prognosis in hepatocellular carcinoma
por: Guan, Qiutong, et al.
Publicado: (2022)

Methyltransferase-Like 3-Mediated m6A Methylation of Hsa_circ_0058493 Accelerates Hepatocellular Carcinoma Progression by Binding to YTH Domain-Containing Protein 1
por: Wu, Anqi, et al.
Publicado: (2021)

METTL16 predicts a favorable outcome and primes antitumor immunity in pancreatic ductal adenocarcinoma
por: Lu, Liting, et al.
Publicado: (2022)

Recent advances in optical aptasensors for biomarkers in early diagnosis and prognosis monitoring of hepatocellular carcinoma
por: Dong, Jia-Mei, et al.
Publicado: (2023)

Elevated levels of the methyltransferase SETD2 causes transcription and alternative splicing changes resulting in oncogenic phenotypes
por: Bhattacharya, Saikat, et al.
Publicado: (2022)

Dynamics of m6A RNA Methylome on the Hallmarks of Hepatocellular Carcinoma
por: Sivasudhan, Enakshi, et al.
Publicado: (2021)

Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma
por: Chen, Shi-lu, et al.
Publicado: (2021)

miR-6807-5p Inhibited the Odontogenic Differentiation of Human Dental Pulp Stem Cells Through Directly Targeting METTL7A
por: Wang, Ning, et al.
Publicado: (2021)

Probing Synergistic Targets by Natural Compounds for Hepatocellular Carcinoma
por: Gao, Jian, et al.
Publicado: (2021)

The Role of Ferroptosis in the Treatment and Drug Resistance of Hepatocellular Carcinoma
por: Zhao, Siqi, et al.
Publicado: (2022)

Bioinformatics Study Revealed Significance of Exosome Transcriptome in Hepatocellular Carcinoma Diagnosis
por: Wu, Zeng-Hong, et al.
Publicado: (2022)

The Therapeutic Potential of Adipose Tissue-Derived Mesenchymal Stem Cells to Enhance Radiotherapy Effects on Hepatocellular Carcinoma
por: Wu, Lingyun, et al.
Publicado: (2019)

A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
por: Yan, Chaojun, et al.
Publicado: (2023)

A novel prognostic prediction model of cuprotosis-related genes signature in hepatocellular carcinoma
por: Shao, Ruo-Nan, et al.
Publicado: (2023)

METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification
por: Zhou, Xinying, et al.
Publicado: (2022)

Comprehensive Analysis of DNA 5-Methylcytosine and N6-Adenine Methylation by Nanopore Sequencing in Hepatocellular Carcinoma
por: Zhang, Lili, et al.
Publicado: (2022)

CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment
por: Zhang, Yinjiang, et al.
Publicado: (2021)

Machine learning identifies exosome features related to hepatocellular carcinoma
por: Zhu, Kai, et al.
Publicado: (2022)

Prostaglandin E2 and Receptors: Insight Into Tumorigenesis, Tumor Progression, and Treatment of Hepatocellular Carcinoma
por: Chen, Chao, et al.
Publicado: (2022)

CREB Ameliorates Osteoarthritis Progression Through Regulating Chondrocytes Autophagy via the miR-373/METTL3/TFEB Axis
por: Zhang, Haibin, et al.
Publicado: (2022)

METTL3-Mediated m(6)A RNA Methylation of ZBTB4 Interferes With Trophoblast Invasion and Maybe Involved in RSA
por: Huang, Nana, et al.
Publicado: (2022)

Corrigendum: METTL3 contributes to osteosarcoma progression by increasing DANCR mRNA stability via m6A modification
por: Zhou, Xinying, et al.
Publicado: (2023)

Targets of histone H3 lysine 9 methyltransferases
por: Levinsky, Aidan J., et al.
Publicado: (2022)

Significance of Liver Zonation in Hepatocellular Carcinoma
por: Yu, Shizhe, et al.
Publicado: (2022)

Histone Methyltransferase SETD1A Induces Epithelial-Mesenchymal Transition to Promote Invasion and Metastasis Through Epigenetic Reprogramming of Snail in Gastric Cancer
por: Wu, Jugang, et al.
Publicado: (2021)

Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms
por: DiNapoli, Sara E., et al.
Publicado: (2022)

Development and validation of a copper-related gene prognostic signature in hepatocellular carcinoma
por: Shi, Haoting, et al.
Publicado: (2023)

Protein Arginine Methyltransferase 5 Functions via Interacting Proteins
por: Liang, Zhenzhen, et al.
Publicado: (2021)

Cubic Membranes Formation in Synchronized Human Hepatocellular Carcinoma Cells Reveals a Possible Role as a Structural Antioxidant Defense System in Cell Cycle Progression
por: Kong, Deqin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j14d7dlg7bfho84ssim289cuel