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Vitamin C Inhibits Blood-Stage Plasmodium Parasites via Oxidative Stress
During the Plasmodium erythrocytic cycle, glucose is taken up by glucose transporters (GLUTs) in red blood cells (RBCs) and supplied to parasites via the Plasmodium hexose transporter. Here, we demonstrate that the glucose uptake pathway in infected RBCs (iRBCs) can be hijacked by vitamin C (Vc). GL...
Autores principales: | Shi, Xiaoyu, Wei, Meng, Xu, Zihao, Liu, Ying, Zhang, Mujia, Lv, Li, Wang, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144511/ https://www.ncbi.nlm.nih.gov/pubmed/34046404 http://dx.doi.org/10.3389/fcell.2021.639944 |
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