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Histamine can be Formed and Degraded in the Human and Mouse Heart

Histamine is metabolized by several enzymes in vitro and in vivo. The relevance of this metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive inotropic effects (PIE) and positive chronotropic effects (PCE) in humans via H(2)-histamine receptors. In transgenic mi...

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Detalles Bibliográficos
Autores principales:	Neumann, Joachim, Grobe, Juliane M., Weisgut, Jacqueline, Schwelberger, Hubert G., Fogel, Wieslawa Agnieszka, Marušáková, Margaréta, Wache, Hartmut, Bähre, Heike, Buchwalow, Igor B., Dhein, Stefan, Hofmann, Britt, Kirchhefer, Uwe, Gergs, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144513/ https://www.ncbi.nlm.nih.gov/pubmed/34045955 http://dx.doi.org/10.3389/fphar.2021.582916

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