Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma

Adaptive MR-guided radiotherapy (MRgRT) is a new treatment paradigm and its role as a non-invasive treatment option for renal cell carcinoma is evolving. The early clinical experience to date shows that real-time plan adaptation based on the daily MRI anatomy can lead to improved target coverage and...

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Autores principales: Keller, Brian, Bruynzeel, Anna M. E., Tang, Chad, Swaminath, Anand, Kerkmeijer, Linda, Chu, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144516/
https://www.ncbi.nlm.nih.gov/pubmed/34046341
http://dx.doi.org/10.3389/fonc.2021.634830
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author Keller, Brian
Bruynzeel, Anna M. E.
Tang, Chad
Swaminath, Anand
Kerkmeijer, Linda
Chu, William
author_facet Keller, Brian
Bruynzeel, Anna M. E.
Tang, Chad
Swaminath, Anand
Kerkmeijer, Linda
Chu, William
author_sort Keller, Brian
collection PubMed
description Adaptive MR-guided radiotherapy (MRgRT) is a new treatment paradigm and its role as a non-invasive treatment option for renal cell carcinoma is evolving. The early clinical experience to date shows that real-time plan adaptation based on the daily MRI anatomy can lead to improved target coverage and normal tissue sparing. Continued technological innovations will further mitigate the challenges of organ motion and enable more advanced treatment adaptation, and potentially lead to enhanced oncologic outcomes and preservation of renal function. Future applications look promising to make a positive clinical impact and further the personalization of radiotherapy in the management of renal cell carcinoma.
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spelling pubmed-81445162021-05-26 Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma Keller, Brian Bruynzeel, Anna M. E. Tang, Chad Swaminath, Anand Kerkmeijer, Linda Chu, William Front Oncol Oncology Adaptive MR-guided radiotherapy (MRgRT) is a new treatment paradigm and its role as a non-invasive treatment option for renal cell carcinoma is evolving. The early clinical experience to date shows that real-time plan adaptation based on the daily MRI anatomy can lead to improved target coverage and normal tissue sparing. Continued technological innovations will further mitigate the challenges of organ motion and enable more advanced treatment adaptation, and potentially lead to enhanced oncologic outcomes and preservation of renal function. Future applications look promising to make a positive clinical impact and further the personalization of radiotherapy in the management of renal cell carcinoma. Frontiers Media S.A. 2021-05-11 /pmc/articles/PMC8144516/ /pubmed/34046341 http://dx.doi.org/10.3389/fonc.2021.634830 Text en Copyright © 2021 Keller, Bruynzeel, Tang, Swaminath, Kerkmeijer and Chu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Keller, Brian
Bruynzeel, Anna M. E.
Tang, Chad
Swaminath, Anand
Kerkmeijer, Linda
Chu, William
Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma
title Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma
title_full Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma
title_fullStr Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma
title_full_unstemmed Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma
title_short Adaptive Magnetic Resonance-Guided Stereotactic Body Radiotherapy: The Next Step in the Treatment of Renal Cell Carcinoma
title_sort adaptive magnetic resonance-guided stereotactic body radiotherapy: the next step in the treatment of renal cell carcinoma
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144516/
https://www.ncbi.nlm.nih.gov/pubmed/34046341
http://dx.doi.org/10.3389/fonc.2021.634830
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