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Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules

We report on the electrical behaviour of thin films of bovine brain microtubules (MTs). For samples in both their dried and hydrated states, the measured currents reveal a power law dependence on the applied DC voltage. We attribute this to the injection of space-charge from the metallic electrode(s...

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Autores principales: Vissol-Gaudin, Eléonore, Pearson, Chris, Groves, Chris, Zeze, Dagou A., Cantiello, Horacio F., Cantero, María del Rocio, Petty, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144580/
https://www.ncbi.nlm.nih.gov/pubmed/34031499
http://dx.doi.org/10.1038/s41598-021-90260-0
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author Vissol-Gaudin, Eléonore
Pearson, Chris
Groves, Chris
Zeze, Dagou A.
Cantiello, Horacio F.
Cantero, María del Rocio
Petty, Michael C.
author_facet Vissol-Gaudin, Eléonore
Pearson, Chris
Groves, Chris
Zeze, Dagou A.
Cantiello, Horacio F.
Cantero, María del Rocio
Petty, Michael C.
author_sort Vissol-Gaudin, Eléonore
collection PubMed
description We report on the electrical behaviour of thin films of bovine brain microtubules (MTs). For samples in both their dried and hydrated states, the measured currents reveal a power law dependence on the applied DC voltage. We attribute this to the injection of space-charge from the metallic electrode(s). The MTs are thought to form a complex electrical network, which can be manipulated with an applied voltage. This feature has been exploited to undertake some experiments on the use of the MT mesh as a medium for computation. We show that it is possible to evolve MT films into binary classifiers following an evolution in materio approach. The accuracy of the system is, on average, similar to that of early carbon nanotube classifiers developed using the same methodology.
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spelling pubmed-81445802021-05-26 Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules Vissol-Gaudin, Eléonore Pearson, Chris Groves, Chris Zeze, Dagou A. Cantiello, Horacio F. Cantero, María del Rocio Petty, Michael C. Sci Rep Article We report on the electrical behaviour of thin films of bovine brain microtubules (MTs). For samples in both their dried and hydrated states, the measured currents reveal a power law dependence on the applied DC voltage. We attribute this to the injection of space-charge from the metallic electrode(s). The MTs are thought to form a complex electrical network, which can be manipulated with an applied voltage. This feature has been exploited to undertake some experiments on the use of the MT mesh as a medium for computation. We show that it is possible to evolve MT films into binary classifiers following an evolution in materio approach. The accuracy of the system is, on average, similar to that of early carbon nanotube classifiers developed using the same methodology. Nature Publishing Group UK 2021-05-24 /pmc/articles/PMC8144580/ /pubmed/34031499 http://dx.doi.org/10.1038/s41598-021-90260-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Vissol-Gaudin, Eléonore
Pearson, Chris
Groves, Chris
Zeze, Dagou A.
Cantiello, Horacio F.
Cantero, María del Rocio
Petty, Michael C.
Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules
title Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules
title_full Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules
title_fullStr Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules
title_full_unstemmed Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules
title_short Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules
title_sort electrical behaviour and evolutionary computation in thin films of bovine brain microtubules
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144580/
https://www.ncbi.nlm.nih.gov/pubmed/34031499
http://dx.doi.org/10.1038/s41598-021-90260-0
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