The metabolic hormone leptin promotes the function of T(FH) cells and supports vaccine responses

Follicular helper T (T(FH)) cells control antibody responses by supporting antibody affinity maturation and memory formation. Inadequate T(FH) function has been found in individuals with ineffective responses to vaccines, but the mechanism underlying T(FH) regulation in vaccination is not understood...

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Detalles Bibliográficos
Autores principales: Deng, Jun, Chen, Qian, Chen, Zhian, Liang, Kaili, Gao, Xin, Wang, Xiaohui, Makota, Fadzai V., Ong, Hong Sheng, Wan, Yanmin, Luo, Kaiming, Gong, Dongcheng, Yu, Xiang, Camuglia, Sarina, Zeng, Qunxiong, Zhou, Tao, Xue, Feng, He, Jing, Wei, Yunbo, Xiao, Fan, Ma, Jianyang, Hill, Danika L., Pierson, Wim, Nguyen, Thi H. O., Zhou, Haibo, Wang, Yan, Shen, Wei, Sun, Lingyun, Li, Zhanguo, Xia, Qiang, Qian, Kun, Ye, Lilin, Rockman, Steven, Linterman, Michelle A., Kedzierska, Katherine, Shen, Nan, Lu, Liwei, Yu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144586/
https://www.ncbi.nlm.nih.gov/pubmed/34031386
http://dx.doi.org/10.1038/s41467-021-23220-x

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