Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility

Unlike other malignancies, therapeutic options in pancreatic ductal adenocarcinoma (PDAC) are largely limited to cytotoxic chemotherapy without the benefit of molecular markers predicting response. Here we report tumor-cell-intrinsic chromatin accessibility patterns of treatment-naïve surgically res...

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Detalles Bibliográficos
Autores principales: Dhara, S., Chhangawala, S., Chintalapudi, H., Askan, G., Aveson, V., Massa, A. L., Zhang, L., Torres, D., Makohon-Moore, A. P., Lecomte, N., Melchor, J. P., Bermeo, J., Cardenas, A., Sinha, S., Glassman, D., Nicolle, R., Moffitt, R., Yu, K. H., Leppanen, S., Laderman, S., Curry, B., Gui, J., Balachandran, V. P., Iacobuzio-Donahue, C., Chandwani, R., Leslie, C. S., Leach, S. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144607/
https://www.ncbi.nlm.nih.gov/pubmed/34031415
http://dx.doi.org/10.1038/s41467-021-23237-2

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