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Recurrent Somatic MAP2K1 Mutations in Papillary Thyroid Cancer and Colorectal Cancer
Mitogen-activated protein kinase kinase 1 (MAP2K1) is a dual specificity protein kinase that phosphorylates both threonine and tyrosine residues in ERK. MAP2K1 mutations have been identified in several cancers. However, their role in Middle Eastern papillary thyroid cancer (PTC) and colorectal cance...
Autores principales: | Bu, Rong, Siraj, Abdul K., Masoodi, Tariq, Parvathareddy, Sandeep Kumar, Iqbal, Kaleem, Al-Rasheed, Maha, Haqawi, Wael, Diaz, Mark, Victoria, Ingrid G., Aldughaither, Saud M., Al-Sobhi, Saif S., Al-Dayel, Fouad, Al-Kuraya, Khawla S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144646/ https://www.ncbi.nlm.nih.gov/pubmed/34046359 http://dx.doi.org/10.3389/fonc.2021.670423 |
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