The multidomain architecture of a bacteriophage endolysin enables intramolecular synergism and regulation of bacterial lysis

Endolysins are peptidoglycan hydrolases produced at the end of the bacteriophage (phage) replication cycle to lyse the host cell. Endolysins in Gram-positive phages come in a variety of multimodular forms that combine different catalytic and cell wall binding domains. However, the reason why phages...

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Detalles Bibliográficos
Autores principales: Oechslin, Frank, Menzi, Carmen, Moreillon, Philippe, Resch, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144678/
https://www.ncbi.nlm.nih.gov/pubmed/33838182
http://dx.doi.org/10.1016/j.jbc.2021.100639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144678/
https://www.ncbi.nlm.nih.gov/pubmed/33838182
http://dx.doi.org/10.1016/j.jbc.2021.100639

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