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The multidomain architecture of a bacteriophage endolysin enables intramolecular synergism and regulation of bacterial lysis
Endolysins are peptidoglycan hydrolases produced at the end of the bacteriophage (phage) replication cycle to lyse the host cell. Endolysins in Gram-positive phages come in a variety of multimodular forms that combine different catalytic and cell wall binding domains. However, the reason why phages...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144678/ https://www.ncbi.nlm.nih.gov/pubmed/33838182 http://dx.doi.org/10.1016/j.jbc.2021.100639 |