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The study of clinical profile and outcome of patients with snakebite in a rural community

CONTEXT: Snakebite remains an underrated cause of accidental death in modern India, primarily in rural India, where people fail to reach out to modern medicine and fall victim to the handful of quacks using traditional healing methods. If promptly diagnosed and treated based on various clinical dete...

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Autores principales: Patel, Samirkumar, Patel, Aayushi, Ganjiwale, Jaishree, Patel, Dhaval, Nimbalkar, Somashekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144800/
https://www.ncbi.nlm.nih.gov/pubmed/34123909
http://dx.doi.org/10.4103/jfmpc.jfmpc_1976_20
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author Patel, Samirkumar
Patel, Aayushi
Ganjiwale, Jaishree
Patel, Dhaval
Nimbalkar, Somashekhar
author_facet Patel, Samirkumar
Patel, Aayushi
Ganjiwale, Jaishree
Patel, Dhaval
Nimbalkar, Somashekhar
author_sort Patel, Samirkumar
collection PubMed
description CONTEXT: Snakebite remains an underrated cause of accidental death in modern India, primarily in rural India, where people fail to reach out to modern medicine and fall victim to the handful of quacks using traditional healing methods. If promptly diagnosed and treated based on various clinical determinants like mode of presentation, time of medical intervention, recognition of the species, and analysis of a series of reliably identified bites, the treatment outcome would be more promising. We aimed to study snakebite patients' clinical profile and treatment outcome in a rural tertiary care setup. MATERIALS AND METHOD: This is a retrospective study in which the data evaluated from an epidemiological viewpoint; gender and age of the snake bite victim, time when bitten, interval between the bite and medical consultation, pattern of toxicity, and response to anti-snake venom (ASV). RESULTS: Of a total of 200 patients bitten by a snake, 121 were males, with 77% adults. In nearly all cases, the type of snake was unknown; however, most of the bites were poisonous, showing one or the other type of toxicity. One hundred seventy-one patients survived the snake bite, and 29 succumbed. When Logistic regression was done with Death/discharge as the dependent variable and “Time to bite and reaching hospital, Age, Sex, number of ASV given, Ventilation needed or not, pack cell volume (PCV) numbers, Fresh Frozen Plasma (FFP) numbers, Dialysis and presence or absence of toxicity” as the independent variables, the model developed did not account for any respectable amount of variation in the outcome. The only variable found to be predicting the outcome significantly was FFP. CONCLUSION: It is often difficult to identify the type of snake, and thus polyvalent antisnake venom remains the only available treatment resource. Readily available treatment resources, timely intervention, appropriate referral, and close ICU will alleviate mortality.
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spelling pubmed-81448002021-06-11 The study of clinical profile and outcome of patients with snakebite in a rural community Patel, Samirkumar Patel, Aayushi Ganjiwale, Jaishree Patel, Dhaval Nimbalkar, Somashekhar J Family Med Prim Care Original Article CONTEXT: Snakebite remains an underrated cause of accidental death in modern India, primarily in rural India, where people fail to reach out to modern medicine and fall victim to the handful of quacks using traditional healing methods. If promptly diagnosed and treated based on various clinical determinants like mode of presentation, time of medical intervention, recognition of the species, and analysis of a series of reliably identified bites, the treatment outcome would be more promising. We aimed to study snakebite patients' clinical profile and treatment outcome in a rural tertiary care setup. MATERIALS AND METHOD: This is a retrospective study in which the data evaluated from an epidemiological viewpoint; gender and age of the snake bite victim, time when bitten, interval between the bite and medical consultation, pattern of toxicity, and response to anti-snake venom (ASV). RESULTS: Of a total of 200 patients bitten by a snake, 121 were males, with 77% adults. In nearly all cases, the type of snake was unknown; however, most of the bites were poisonous, showing one or the other type of toxicity. One hundred seventy-one patients survived the snake bite, and 29 succumbed. When Logistic regression was done with Death/discharge as the dependent variable and “Time to bite and reaching hospital, Age, Sex, number of ASV given, Ventilation needed or not, pack cell volume (PCV) numbers, Fresh Frozen Plasma (FFP) numbers, Dialysis and presence or absence of toxicity” as the independent variables, the model developed did not account for any respectable amount of variation in the outcome. The only variable found to be predicting the outcome significantly was FFP. CONCLUSION: It is often difficult to identify the type of snake, and thus polyvalent antisnake venom remains the only available treatment resource. Readily available treatment resources, timely intervention, appropriate referral, and close ICU will alleviate mortality. Wolters Kluwer - Medknow 2021-04 2021-04-29 /pmc/articles/PMC8144800/ /pubmed/34123909 http://dx.doi.org/10.4103/jfmpc.jfmpc_1976_20 Text en Copyright: © 2021 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Patel, Samirkumar
Patel, Aayushi
Ganjiwale, Jaishree
Patel, Dhaval
Nimbalkar, Somashekhar
The study of clinical profile and outcome of patients with snakebite in a rural community
title The study of clinical profile and outcome of patients with snakebite in a rural community
title_full The study of clinical profile and outcome of patients with snakebite in a rural community
title_fullStr The study of clinical profile and outcome of patients with snakebite in a rural community
title_full_unstemmed The study of clinical profile and outcome of patients with snakebite in a rural community
title_short The study of clinical profile and outcome of patients with snakebite in a rural community
title_sort study of clinical profile and outcome of patients with snakebite in a rural community
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144800/
https://www.ncbi.nlm.nih.gov/pubmed/34123909
http://dx.doi.org/10.4103/jfmpc.jfmpc_1976_20
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