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Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus

Neutrophil activation and the formation of neutrophil extracellular traps (NETs) are hallmarks of innate immune activation in systemic lupus erythematosus (SLE). Here we report that the expression of an endogenous retrovirus (ERV) locus ERV-K102, encoding an envelope protein, was significantly eleva...

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Detalles Bibliográficos
Autores principales: Tokuyama, Maria, Gunn, Bronwyn M., Venkataraman, Arvind, Kong, Yong, Kang, Insoo, Rakib, Tasfia, Townsend, Michael J., Costenbader, Karen H., Alter, Galit, Iwasaki, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144942/
https://www.ncbi.nlm.nih.gov/pubmed/34019642
http://dx.doi.org/10.1084/jem.20191766