COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials

Various strategies have been designed to contain the COVID-19 pandemic. Among them, vaccine development is high on the agenda in spite of the unknown duration of the protection time. Various vaccines have been under clinical trials with promising results in different countries. The protective effica...

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Detalles Bibliográficos
Autores principales: Yan, Zhi-Peng, Yang, Ming, Lai, Ching-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144958/
https://www.ncbi.nlm.nih.gov/pubmed/33923054
http://dx.doi.org/10.3390/ph14050406
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author Yan, Zhi-Peng
Yang, Ming
Lai, Ching-Lung
author_facet Yan, Zhi-Peng
Yang, Ming
Lai, Ching-Lung
author_sort Yan, Zhi-Peng
collection PubMed
description Various strategies have been designed to contain the COVID-19 pandemic. Among them, vaccine development is high on the agenda in spite of the unknown duration of the protection time. Various vaccines have been under clinical trials with promising results in different countries. The protective efficacy and the short-term and long-term side effects of the vaccines are of major concern. Therefore, comparing the protective efficacy and risks of vaccination is essential for the global control of COVID-19 through herd immunity. This study reviews the most recent data of 12 vaccines to evaluate their efficacy, safety profile and usage in various populations.
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spelling pubmed-81449582021-05-26 COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials Yan, Zhi-Peng Yang, Ming Lai, Ching-Lung Pharmaceuticals (Basel) Review Various strategies have been designed to contain the COVID-19 pandemic. Among them, vaccine development is high on the agenda in spite of the unknown duration of the protection time. Various vaccines have been under clinical trials with promising results in different countries. The protective efficacy and the short-term and long-term side effects of the vaccines are of major concern. Therefore, comparing the protective efficacy and risks of vaccination is essential for the global control of COVID-19 through herd immunity. This study reviews the most recent data of 12 vaccines to evaluate their efficacy, safety profile and usage in various populations. MDPI 2021-04-25 /pmc/articles/PMC8144958/ /pubmed/33923054 http://dx.doi.org/10.3390/ph14050406 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yan, Zhi-Peng
Yang, Ming
Lai, Ching-Lung
COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
title COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
title_full COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
title_fullStr COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
title_full_unstemmed COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
title_short COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
title_sort covid-19 vaccines: a review of the safety and efficacy of current clinical trials
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144958/
https://www.ncbi.nlm.nih.gov/pubmed/33923054
http://dx.doi.org/10.3390/ph14050406
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