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In Vitro Evaluation of CD276-CAR NK-92 Functionality, Migration and Invasion Potential in the Presence of Immune Inhibitory Factors of the Tumor Microenvironment
Background: Melanoma is the most lethal of all skin-related cancers with incidences continuously rising. Novel therapeutic approaches are urgently needed, especially for the treatment of metastasizing or therapy-resistant melanoma. CAR-modified immune cells have shown excellent results in treating h...
Autores principales: | Grote, Stefan, Ureña-Bailén, Guillermo, Chan, Kenneth Chun-Ho, Baden, Caroline, Mezger, Markus, Handgretinger, Rupert, Schleicher, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145105/ https://www.ncbi.nlm.nih.gov/pubmed/33925968 http://dx.doi.org/10.3390/cells10051020 |
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