Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes

Herein, we report a protein-based hybridization strategy that exploits the host-guest chemistry of HSA (human serum albumin) to solubilize the otherwise cell impermeable ONOO(−) fluorescent probe Pinkment-OAc. Formation of a HSA/Pinkment-OAc supramolecular hybrid was confirmed by SAXS and solution-s...

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Detalles Bibliográficos
Autores principales: Han, Hai-Hao, Sedgwick, Adam C., Shang, Ying, Li, Na, Liu, Tingting, Li, Bo-Han, Yu, Kunqian, Zang, Yi, Brewster, James T., Odyniec, Maria L., Weber, Maria, Bull, Steven D., Li, Jia, Sessler, Jonathan L., James, Tony D., He, Xiao-Peng, Tian, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145178/
https://www.ncbi.nlm.nih.gov/pubmed/34084367
http://dx.doi.org/10.1039/c9sc03961a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145178/
https://www.ncbi.nlm.nih.gov/pubmed/34084367
http://dx.doi.org/10.1039/c9sc03961a

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