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Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes
Herein, we report a protein-based hybridization strategy that exploits the host-guest chemistry of HSA (human serum albumin) to solubilize the otherwise cell impermeable ONOO(−) fluorescent probe Pinkment-OAc. Formation of a HSA/Pinkment-OAc supramolecular hybrid was confirmed by SAXS and solution-s...
Autores principales: | Han, Hai-Hao, Sedgwick, Adam C., Shang, Ying, Li, Na, Liu, Tingting, Li, Bo-Han, Yu, Kunqian, Zang, Yi, Brewster, James T., Odyniec, Maria L., Weber, Maria, Bull, Steven D., Li, Jia, Sessler, Jonathan L., James, Tony D., He, Xiao-Peng, Tian, He |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145178/ https://www.ncbi.nlm.nih.gov/pubmed/34084367 http://dx.doi.org/10.1039/c9sc03961a |
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