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Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets

Reducing the use of antibiotics in livestock in order to contain antibiotic resistance and studying natural substance additives are key to sustainability. Among the various biological activities of plant extracts, antioxidant activity plays an important role. The present study assesses the total ant...

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Autores principales: Corino, Carlo, Prost, Michel, Pizzi, Barbara, Rossi, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145250/
https://www.ncbi.nlm.nih.gov/pubmed/33946752
http://dx.doi.org/10.3390/antiox10050702
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author Corino, Carlo
Prost, Michel
Pizzi, Barbara
Rossi, Raffaella
author_facet Corino, Carlo
Prost, Michel
Pizzi, Barbara
Rossi, Raffaella
author_sort Corino, Carlo
collection PubMed
description Reducing the use of antibiotics in livestock in order to contain antibiotic resistance and studying natural substance additives are key to sustainability. Among the various biological activities of plant extracts, antioxidant activity plays an important role. The present study assesses the total antioxidant activity and antioxidant reserves using the Kit Radicaux Libres test (KRL™ Kirial International, Couternon, France). One hundred and sixty piglets (Topics × Tempo) weaned at 28 days of age were divided into four dietary treatment groups that were fed a commercial diet (the control group, C); 500 mg/kg Boswellia extract (BOS); 200 and 50 mg/kg Uncaria and Tanacetum extracts (UT) respectively; and 225 mg/kg of an antioxidant plant extract mixture (AOX). The blood antioxidant activity of the piglets was measured using the KRL test and the reserves were analyzed on whole blood samples after hydrolysis with glucosidase, sulfatase and glucuronidase. No significant differences were observed in growth performance. The delta KRL values of the whole blood showed a significantly higher total antioxidant status of the piglets from the BOS and AOX groups than the UT and C groups (+30.7 BOS; +27.7 AOX vs. +17.81 UT +13.30 C; p = 0.002) between 18 and 28 days post-weaning. The delta KRL values of red blood cells (RBCs) showed a significantly higher total antioxidant status of the piglets from the AOX groups than the UT and BOS groups (+22.2 AOX; vs. +9.90 UT +9.4 BOS; p = 0.016) between the two sampling times. Reserves of UT and AOX were higher than C and BOS for all enzymes, glucosides, sulphates, and glucuronides. The biological KRL test proved to be an extremely sensitive tool to evaluate the piglets’ antioxidant status. Determining the antioxidant reserve also provides a better understanding of the real antioxidant status of pigs.
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spelling pubmed-81452502021-05-26 Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets Corino, Carlo Prost, Michel Pizzi, Barbara Rossi, Raffaella Antioxidants (Basel) Article Reducing the use of antibiotics in livestock in order to contain antibiotic resistance and studying natural substance additives are key to sustainability. Among the various biological activities of plant extracts, antioxidant activity plays an important role. The present study assesses the total antioxidant activity and antioxidant reserves using the Kit Radicaux Libres test (KRL™ Kirial International, Couternon, France). One hundred and sixty piglets (Topics × Tempo) weaned at 28 days of age were divided into four dietary treatment groups that were fed a commercial diet (the control group, C); 500 mg/kg Boswellia extract (BOS); 200 and 50 mg/kg Uncaria and Tanacetum extracts (UT) respectively; and 225 mg/kg of an antioxidant plant extract mixture (AOX). The blood antioxidant activity of the piglets was measured using the KRL test and the reserves were analyzed on whole blood samples after hydrolysis with glucosidase, sulfatase and glucuronidase. No significant differences were observed in growth performance. The delta KRL values of the whole blood showed a significantly higher total antioxidant status of the piglets from the BOS and AOX groups than the UT and C groups (+30.7 BOS; +27.7 AOX vs. +17.81 UT +13.30 C; p = 0.002) between 18 and 28 days post-weaning. The delta KRL values of red blood cells (RBCs) showed a significantly higher total antioxidant status of the piglets from the AOX groups than the UT and BOS groups (+22.2 AOX; vs. +9.90 UT +9.4 BOS; p = 0.016) between the two sampling times. Reserves of UT and AOX were higher than C and BOS for all enzymes, glucosides, sulphates, and glucuronides. The biological KRL test proved to be an extremely sensitive tool to evaluate the piglets’ antioxidant status. Determining the antioxidant reserve also provides a better understanding of the real antioxidant status of pigs. MDPI 2021-04-29 /pmc/articles/PMC8145250/ /pubmed/33946752 http://dx.doi.org/10.3390/antiox10050702 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Corino, Carlo
Prost, Michel
Pizzi, Barbara
Rossi, Raffaella
Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets
title Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets
title_full Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets
title_fullStr Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets
title_full_unstemmed Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets
title_short Dietary Plant Extracts Improve the Antioxidant Reserves in Weaned Piglets
title_sort dietary plant extracts improve the antioxidant reserves in weaned piglets
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145250/
https://www.ncbi.nlm.nih.gov/pubmed/33946752
http://dx.doi.org/10.3390/antiox10050702
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AT rossiraffaella dietaryplantextractsimprovetheantioxidantreservesinweanedpiglets