Cargando…
Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd
Equid herpesvirus type 1 (EHV-1) causes several outbreaks of abortion and/or equid herpesvirus-associated myeloencephalopathy (EHM) worldwide each year. EHM is of great concern, as permanent neurological gait anomalies can leave a horse unfit for future use. The study assesses the risk factors assoc...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145278/ https://www.ncbi.nlm.nih.gov/pubmed/33947126 http://dx.doi.org/10.3390/pathogens10050537 |
_version_ | 1783697136637968384 |
---|---|
author | Klouth, Eva Zablotski, Yury Goehring, Lutz S. |
author_facet | Klouth, Eva Zablotski, Yury Goehring, Lutz S. |
author_sort | Klouth, Eva |
collection | PubMed |
description | Equid herpesvirus type 1 (EHV-1) causes several outbreaks of abortion and/or equid herpesvirus-associated myeloencephalopathy (EHM) worldwide each year. EHM is of great concern, as permanent neurological gait anomalies can leave a horse unfit for future use. The study assesses the risk factors associated with the occurrence of EHM. During an unmitigated outbreak, 141 adult horses/ponies of several distinct breeds were evaluated—using multiple Bayesian logistic regression calculating the odds ratios for breed, age, and sex. In total, 33 of the 141 horses showed signs of EHM. Fjord horses and warmblood horses were overrepresented among those developing EHM. The pony breeds, Welsh and Shetland ponies, were underrepresented. In addition, age and sex were not associated with the risk for EHM. The main limitation was that it was a retrospective analysis with some flaws of documentation. It can be concluded that breed was a significant risk factor for developing EHM during this outbreak. |
format | Online Article Text |
id | pubmed-8145278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81452782021-05-26 Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd Klouth, Eva Zablotski, Yury Goehring, Lutz S. Pathogens Article Equid herpesvirus type 1 (EHV-1) causes several outbreaks of abortion and/or equid herpesvirus-associated myeloencephalopathy (EHM) worldwide each year. EHM is of great concern, as permanent neurological gait anomalies can leave a horse unfit for future use. The study assesses the risk factors associated with the occurrence of EHM. During an unmitigated outbreak, 141 adult horses/ponies of several distinct breeds were evaluated—using multiple Bayesian logistic regression calculating the odds ratios for breed, age, and sex. In total, 33 of the 141 horses showed signs of EHM. Fjord horses and warmblood horses were overrepresented among those developing EHM. The pony breeds, Welsh and Shetland ponies, were underrepresented. In addition, age and sex were not associated with the risk for EHM. The main limitation was that it was a retrospective analysis with some flaws of documentation. It can be concluded that breed was a significant risk factor for developing EHM during this outbreak. MDPI 2021-04-29 /pmc/articles/PMC8145278/ /pubmed/33947126 http://dx.doi.org/10.3390/pathogens10050537 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Klouth, Eva Zablotski, Yury Goehring, Lutz S. Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd |
title | Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd |
title_full | Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd |
title_fullStr | Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd |
title_full_unstemmed | Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd |
title_short | Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd |
title_sort | apparent breed predilection for equid herpesvirus-1-associated myeloencephalopathy (ehm) in a multiple-breed herd |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145278/ https://www.ncbi.nlm.nih.gov/pubmed/33947126 http://dx.doi.org/10.3390/pathogens10050537 |
work_keys_str_mv | AT kloutheva apparentbreedpredilectionforequidherpesvirus1associatedmyeloencephalopathyehminamultiplebreedherd AT zablotskiyury apparentbreedpredilectionforequidherpesvirus1associatedmyeloencephalopathyehminamultiplebreedherd AT goehringlutzs apparentbreedpredilectionforequidherpesvirus1associatedmyeloencephalopathyehminamultiplebreedherd |