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Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT)

SIMPLE SUMMARY: The metallic implants carry many problems as infections, bone resorption, pain at the site, etc. Removing these metallic implants is an expensive procedure, and it entails risks. Due to the costs, the most common in veterinary medicine is to remove metallic implants only when a probl...

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Autores principales: Valiño-Cultelli, Victoria, Varela-López, Óscar, González-Cantalapiedra, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145287/
https://www.ncbi.nlm.nih.gov/pubmed/33925099
http://dx.doi.org/10.3390/ani11051271
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author Valiño-Cultelli, Victoria
Varela-López, Óscar
González-Cantalapiedra, Antonio
author_facet Valiño-Cultelli, Victoria
Varela-López, Óscar
González-Cantalapiedra, Antonio
author_sort Valiño-Cultelli, Victoria
collection PubMed
description SIMPLE SUMMARY: The metallic implants carry many problems as infections, bone resorption, pain at the site, etc. Removing these metallic implants is an expensive procedure, and it entails risks. Due to the costs, the most common in veterinary medicine is to remove metallic implants only when a problem occurs. The rupture of the cranial cruciate ligament (RCrCL) is the most common orthopedic pathology in dogs and the most frequent cause of arthrosis, pain, and limp on the knee joint. Those are the reasons that encouraged us to develop a new type of biodegradable implant comprised of polylactic acid (PLA). This is a non-toxic material that can be eliminated by natural metabolic pathways and use the PLA implant in tibial tuberosity advancement (TTA), which is a technique for the resolution of RCrCL in dogs. In our study, PLA implants for TTA provide good functional results, presenting an acceptable number of complications. The implants show a faster ossification than metallic implants, which was not affected by age or by body weight. The PLA implants have a clinical recovery time similar to metallic implants. ABSTRACT: Our objectives were to determine whether PLA implants can be used in TTA with successful results; secondly, to observe whether they provide a faster bone healing; finally, to determine whether weight or age influences bone healing scores. PLA cages were created with a 3D printer. TTA by MMT with PLA implants was performed in 24 patients. Follow-ups were carried out pre-surgical, at 1, 2, and 5 months and consisted of a radiographic study and a lameness assessment. A comparison was performed in terms of weight and age. Patients data, time between follow-up examinations, healing score, and lameness score were compared between patients using commercial software for statistically significant differences p < 0.05. Eighteen dogs finished the study. The ossification degrees presented statistically significant differences between each other. PLA implants maintained the advancement in 100% of cases. Comparing weight and age did not present any statistically significant differences between groups. Lameness presented statistically significant differences between follow-up examinations. Complications were observed in 20.8%. PLA implants for TTA provide good functional results, presenting an acceptable rate of complications. They provide a faster bone healing of the osteotomy gap, which was not affected by age or body weight, and have a clinical recovery time similar to metallic implants.
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spelling pubmed-81452872021-05-26 Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT) Valiño-Cultelli, Victoria Varela-López, Óscar González-Cantalapiedra, Antonio Animals (Basel) Article SIMPLE SUMMARY: The metallic implants carry many problems as infections, bone resorption, pain at the site, etc. Removing these metallic implants is an expensive procedure, and it entails risks. Due to the costs, the most common in veterinary medicine is to remove metallic implants only when a problem occurs. The rupture of the cranial cruciate ligament (RCrCL) is the most common orthopedic pathology in dogs and the most frequent cause of arthrosis, pain, and limp on the knee joint. Those are the reasons that encouraged us to develop a new type of biodegradable implant comprised of polylactic acid (PLA). This is a non-toxic material that can be eliminated by natural metabolic pathways and use the PLA implant in tibial tuberosity advancement (TTA), which is a technique for the resolution of RCrCL in dogs. In our study, PLA implants for TTA provide good functional results, presenting an acceptable number of complications. The implants show a faster ossification than metallic implants, which was not affected by age or by body weight. The PLA implants have a clinical recovery time similar to metallic implants. ABSTRACT: Our objectives were to determine whether PLA implants can be used in TTA with successful results; secondly, to observe whether they provide a faster bone healing; finally, to determine whether weight or age influences bone healing scores. PLA cages were created with a 3D printer. TTA by MMT with PLA implants was performed in 24 patients. Follow-ups were carried out pre-surgical, at 1, 2, and 5 months and consisted of a radiographic study and a lameness assessment. A comparison was performed in terms of weight and age. Patients data, time between follow-up examinations, healing score, and lameness score were compared between patients using commercial software for statistically significant differences p < 0.05. Eighteen dogs finished the study. The ossification degrees presented statistically significant differences between each other. PLA implants maintained the advancement in 100% of cases. Comparing weight and age did not present any statistically significant differences between groups. Lameness presented statistically significant differences between follow-up examinations. Complications were observed in 20.8%. PLA implants for TTA provide good functional results, presenting an acceptable rate of complications. They provide a faster bone healing of the osteotomy gap, which was not affected by age or body weight, and have a clinical recovery time similar to metallic implants. MDPI 2021-04-28 /pmc/articles/PMC8145287/ /pubmed/33925099 http://dx.doi.org/10.3390/ani11051271 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Valiño-Cultelli, Victoria
Varela-López, Óscar
González-Cantalapiedra, Antonio
Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT)
title Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT)
title_full Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT)
title_fullStr Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT)
title_full_unstemmed Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT)
title_short Preliminary Clinical and Radiographic Evaluation of a Novel Resorbable Implant of Polylactic Acid (PLA) for Tibial Tuberosity Advancement (TTA) by Modified Maquet Technique (MMT)
title_sort preliminary clinical and radiographic evaluation of a novel resorbable implant of polylactic acid (pla) for tibial tuberosity advancement (tta) by modified maquet technique (mmt)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145287/
https://www.ncbi.nlm.nih.gov/pubmed/33925099
http://dx.doi.org/10.3390/ani11051271
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