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Mind the Gap: LRRK2 Phenotypes in the Clinic vs. in Patient Cells
Mutations in the Parkinson’s disease (PD) protein Leucine Rich Repeat Kinase 2 (LRRK2) have been under study for more than 15 years and our understanding of the cellular phenotypes for the pathogenic mutant forms of LRRK2 has significantly advanced. In parallel to research on LRRK2 mutations in expe...
Autores principales: | Goveas, Liesel, Mutez, Eugénie, Chartier-Harlin, Marie-Christine, Taymans, Jean-Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145309/ https://www.ncbi.nlm.nih.gov/pubmed/33922322 http://dx.doi.org/10.3390/cells10050981 |
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