Cargando…

DNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells

The application of physiological oxygen (physoxia) concentrations is becoming increasingly commonplace within a mammalian stem cell culture. Human mesenchymal stem cells (hMSCs) attract widespread interest for clinical application due to their unique immunomodulatory, multi-lineage potential, and re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dogan, Fatma, Aljumaily, Rakad M Kh, Kitchen, Mark, Forsyth, Nicholas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145390/ https://www.ncbi.nlm.nih.gov/pubmed/33925659 http://dx.doi.org/10.3390/cells10051032

Ejemplares similares

Physoxia Influences Global and Gene-Specific Methylation in Pluripotent Stem Cells
por: Dogan, Fatma, et al.
Publicado: (2022)

Hypoxia-Modified Cancer Cell Metabolism
por: Al Tameemi, Wafaa, et al.
Publicado: (2019)

The ‘de novo’ DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium
por: Elliott, Ellen N, et al.
Publicado: (2016)

De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells
por: Fukuda, Atsushi, et al.
Publicado: (2021)

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
por: Liao, Jing, et al.
Publicado: (2015)

Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development
por: Yagi, Masaki, et al.
Publicado: (2020)

The localization of protein carboxyl-methylase in sperm tails
Publicado: (1980)

Regulation of Methylase METTL3 on Fat Deposition
por: Luo, Gang, et al.
Publicado: (2021)

Structure and Catalytic Mechanism of Radical SAM Methylases
por: Nguyen, Tu-Quynh, et al.
Publicado: (2022)

The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1
por: Hsieh, Chih-Lin
Publicado: (2005)

Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
por: Meilinger, Daniela, et al.
Publicado: (2009)

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
por: Gao, Linfeng, et al.
Publicado: (2020)

Inactive DNMT3B Splice Variants Modulate De Novo DNA Methylation
por: Gordon, Catherine A., et al.
Publicado: (2013)

Regulation of histone arginine methylation/demethylation by methylase and demethylase
por: Zhang, Jing, et al.
Publicado: (2019)

ODP207 Histone methylase MLL attenuates insulin secretion by reducing glucose sensitivity in mouse pancreas
por: Yoshino, Satoshi, et al.
Publicado: (2022)

Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
por: Van Emburgh, Beth O., et al.
Publicado: (2011)

The m(6)A‑methylase complex and mRNA export()
por: Lesbirel, Simon, et al.
Publicado: (2019)

Methylase-assisted subcloning for high throughput BioBrick assembly
por: Matsumura, Ichiro
Publicado: (2020)

Dnmt1 has de novo activity targeted to transposable elements
por: Haggerty, Chuck, et al.
Publicado: (2021)

METTL3‐m(6) A methylase regulates the osteogenic potential of bone marrow mesenchymal stem cells in osteoporotic rats via the Wnt signalling pathway
por: Wu, Tianli, et al.
Publicado: (2022)

Telomerase Regulation: A Role for Epigenetics
por: Dogan, Fatma, et al.
Publicado: (2021)

16S rRNA Methylase–producing, Gram-Negative Pathogens, Japan
por: Yamane, Kunikazu, et al.
Publicado: (2007)

An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis
por: Chen, Wenqing, et al.
Publicado: (2016)

Genome-Wide Identification of DNA Methylases and Demethylases in Kiwifruit (Actinidia chinensis)
por: Zhang, Yaoxin, et al.
Publicado: (2020)

The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development
por: Fittipaldi, Raffaella, et al.
Publicado: (2021)

m(6)A Methylases Regulate Myoblast Proliferation, Apoptosis and Differentiation
por: Yang, Xinran, et al.
Publicado: (2022)

PRMT5: A novel regulator of Hepatitis B virus replication and an arginine methylase of HBV core
por: Lubyova, Barbora, et al.
Publicado: (2017)

Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B
por: Andrews, Simon, et al.
Publicado: (2023)

Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia
por: Wong, Kah Keng, et al.
Publicado: (2019)

Structural basis for DNMT3A-mediated de novo DNA methylation
por: Zhang, Zhi-Min, et al.
Publicado: (2018)

Watasemycin biosynthesis in Streptomyces venezuelae: thiazoline C-methylation by a type B radical-SAM methylase homologue
por: Inahashi, Yuki, et al.
Publicado: (2017)

DNMT3A and DNMT3B in Breast Tumorigenesis and Potential Therapy
por: Man, Xiaxia, et al.
Publicado: (2022)

Essential role of Salmonella Enteritidis DNA adenine methylase in modulating inflammasome activation
por: Guo, Yaxin, et al.
Publicado: (2020)

Regulation of Adipocyte Differentiation by METTL4, a 6 mA Methylase
por: Zhang, Zhenxi, et al.
Publicado: (2020)

Histone Methylases and Demethylases Regulating Antagonistic Methyl Marks: Changes Occurring in Cancer
por: Taylor-Papadimitriou, Joyce, et al.
Publicado: (2022)

Analysis of Novel Histone Methylase MLL Function for Glucose Metabolism in Mouse Pancreas
por: Yoshino, Satoshi, et al.
Publicado: (2021)

The role of histone methylase and demethylase in antitumor immunity: A new direction for immunotherapy
por: Zhang, Yuanling, et al.
Publicado: (2023)

DNMT1, DNMT3A and DNMT3B gene variants in relation to ovarian cancer risk in the Polish population
por: Mostowska, Adrianna, et al.
Publicado: (2013)

Physoxia alters human mesenchymal stem cell secretome
por: Merkhan, Marwan M, et al.
Publicado: (2021)

MEK/ERK and PI3K/AKT pathway inhibitors affect the transformation of myelodysplastic syndrome into acute myeloid leukemia via H3K27me3 methylases and de-methylases
por: Zheng, Zhuanzhen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_67e4f6hc2hnaepdf1d9l3jlneh