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Development of a Virtual Chinese Pediatric Population Physiological Model Targeting Specific Metabolism and Kidney Elimination Pathways

Background: Physiologically based pharmacokinetic (PBPK) modeling and simulating may be a powerful tool in predicting drug behaviors in specific populations. It is a mathematical model that relates the pharmacokinetic (PK) profile of a compound with human anatomical characteristics, physiological ch...

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Detalles Bibliográficos
Autores principales:	Yao, Xueting, Liu, Xuanlin, Tu, Siqi, Li, Xiaobei, Lei, Zihan, Hou, Zhe, Yu, Zhiheng, Cui, Cheng, Dong, Zhongqi, Salem, Farzaneh, Li, Haiyan, Liu, Dongyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145459/ https://www.ncbi.nlm.nih.gov/pubmed/34045960 http://dx.doi.org/10.3389/fphar.2021.648697

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