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Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria

The natural occurrence of six major ergot alkaloids, ergometrine, ergosine, ergotamine, ergocornine, ergokryptine and ergocristine, as well as their corresponding epimers, were investigated in 60 cereal samples (barley and wheat) from Algeria. Ultra-high performance liquid chromatography coupled to...

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Autores principales: Carbonell-Rozas, Laura, Mahdjoubi, Choukri Khelifa, Arroyo-Manzanares, Natalia, García-Campaña, Ana M., Gámiz-Gracia, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145663/
https://www.ncbi.nlm.nih.gov/pubmed/33925104
http://dx.doi.org/10.3390/toxins13050316
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author Carbonell-Rozas, Laura
Mahdjoubi, Choukri Khelifa
Arroyo-Manzanares, Natalia
García-Campaña, Ana M.
Gámiz-Gracia, Laura
author_facet Carbonell-Rozas, Laura
Mahdjoubi, Choukri Khelifa
Arroyo-Manzanares, Natalia
García-Campaña, Ana M.
Gámiz-Gracia, Laura
author_sort Carbonell-Rozas, Laura
collection PubMed
description The natural occurrence of six major ergot alkaloids, ergometrine, ergosine, ergotamine, ergocornine, ergokryptine and ergocristine, as well as their corresponding epimers, were investigated in 60 cereal samples (barley and wheat) from Algeria. Ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) and a QuEChERS extraction method were used for sample analysis. The results revealed that 12 out of 60 samples (20%) were contaminated with ergot alkaloids. Wheat was the most contaminated matrix, with an incidence of 26.7% (8 out of 30 samples). The concentration of total ergot alkaloids ranged from 17.8 to 53.9 µg/kg for barley and from 3.66 to 76.0 μg/kg for wheat samples. Ergosine, ergokryptine and ergocristine showed the highest incidences in wheat, while ergometrine was the most common ergot in barley.
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spelling pubmed-81456632021-05-26 Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria Carbonell-Rozas, Laura Mahdjoubi, Choukri Khelifa Arroyo-Manzanares, Natalia García-Campaña, Ana M. Gámiz-Gracia, Laura Toxins (Basel) Article The natural occurrence of six major ergot alkaloids, ergometrine, ergosine, ergotamine, ergocornine, ergokryptine and ergocristine, as well as their corresponding epimers, were investigated in 60 cereal samples (barley and wheat) from Algeria. Ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) and a QuEChERS extraction method were used for sample analysis. The results revealed that 12 out of 60 samples (20%) were contaminated with ergot alkaloids. Wheat was the most contaminated matrix, with an incidence of 26.7% (8 out of 30 samples). The concentration of total ergot alkaloids ranged from 17.8 to 53.9 µg/kg for barley and from 3.66 to 76.0 μg/kg for wheat samples. Ergosine, ergokryptine and ergocristine showed the highest incidences in wheat, while ergometrine was the most common ergot in barley. MDPI 2021-04-28 /pmc/articles/PMC8145663/ /pubmed/33925104 http://dx.doi.org/10.3390/toxins13050316 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Carbonell-Rozas, Laura
Mahdjoubi, Choukri Khelifa
Arroyo-Manzanares, Natalia
García-Campaña, Ana M.
Gámiz-Gracia, Laura
Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria
title Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria
title_full Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria
title_fullStr Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria
title_full_unstemmed Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria
title_short Occurrence of Ergot Alkaloids in Barley and Wheat from Algeria
title_sort occurrence of ergot alkaloids in barley and wheat from algeria
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145663/
https://www.ncbi.nlm.nih.gov/pubmed/33925104
http://dx.doi.org/10.3390/toxins13050316
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